NCT04839887 Factors Affecting the Quality of Life After Ischemic Stroke in Young Adults
| NCT ID | NCT04839887 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Elena Gurkova |
| Condition | Ischemic Stroke |
| Study Type | OBSERVATIONAL |
| Enrollment | 520 participants |
| Start Date | 2021-03-01 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 520 participants in total. It began in 2021-03-01 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Despite a generally favourable 3-month functional outcome and a very low mortality, young ischemic stroke (IS) patients face to reduced quality of life associated with a complexity of problems or "invisible dysfunctions" after IS. Better identification and understanding to these factors may improve stroke rehabilitation and stroke self-management programmes, wich will lead to better stroke recovery. The aim of the study is to assess the predictors of the health-related quality of life in young patients under 50 years after ischemic stroke, and to to evaluate specific changes in different dimensions of health-related quality of life during the first year of post-stroke recovery using a standardized battery of neuropsychological tools and stroke specific health-related quality of life measures. In the first phase of the study, 300 IS patients will be enrolled for the validation of the Czech version of the the Stroke Impact Scale 3.0. In the second phase of study, 200 enrolled IS patients (100 young IS patients \< 50 years and 100 IS patients of 50-65 years) will undergo a serial of structured and standardized questionnaires during scheduled outpatients' controls three, six and 12 months after IS. In the third phase of study, twenty young IS patients \< 50 years will undergo an in-depth, semi-structured interview with explanatory questions that will allow a detailed understanding of the patient's experience. Interpretative phenomenological analysis (IPA) study design will be used.
Eligibility Criteria
Inclusion Criteria: * Acute ischemic stroke * Age 18-65 years Exclusion Criteria: * Transient ischemic attack without progression to ischemic stroke * Haemorrhagic stroke * Severe cognitive impairment * Severe communication disorder (sensory aphasia with the inability to understand having been verified by a certified speech therapist) * Concomitant severe systemic illness * Impaired ability to understand the questionnaires
Contact & Investigator
Elena Gurkova, PhD
PRINCIPAL INVESTIGATOR
Palacky University, Faculty of Health Sciences, Department of Nursing
Frequently Asked Questions
Who can join the NCT04839887 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Ischemic Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04839887 currently recruiting?
Yes, NCT04839887 is actively recruiting participants. Contact the research team at elena.gurkova@upol.cz for enrollment information.
Where is the NCT04839887 trial being conducted?
This trial is being conducted at Olomouc, Czechia.
Who is sponsoring the NCT04839887 clinical trial?
NCT04839887 is sponsored by Elena Gurkova. The principal investigator is Elena Gurkova, PhD at Palacky University, Faculty of Health Sciences, Department of Nursing. The trial plans to enroll 520 participants.
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