NCT05708911 External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing
| NCT ID | NCT05708911 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical College of Wisconsin |
| Condition | Dysphagia |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2014-09-16 |
| Primary Completion | 2026-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2014-09-16 with a primary completion date of 2026-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study of healthy young and elderly individuals is intended to assess the effects of pharyngeal exerciser on pharyngeal pressure phenomenon during swallowing. Our specific aim is to test if the pharyngeal exerciser increases the workload of muscles involved in pharyngeal phase of swallowing.
Eligibility Criteria
Inclusion Criteria: * Healthy volunteers must be at least 18 years of age or older. Exclusion Criteria: * Subjects with cervical spine disorders. * Subjects with neurological disorders like dementia, cerebrovascular diseases other than Parkinson's Disease * Subjects with carotid artery bruit or carotid vascular disorders. * Subjects suffering from muscle diseases like muscular dystrophies, myopathies. * Subjects with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders. * Subjects with any current esophageal symptoms like heartburn, dysphagia, chest pain or regurgitation. * Subjects cannot have previous head or neck surgery or radiation. * Subjects unable to tolerate nasal intubation. * Subjects with significant bleeding disorders for whom nasal intubation has been deemed contraindicated. * Subjects with a known upper airway or esophageal obstruction preventing the passage of the manometry probe. * Subjects with autonomic dysfunction. * Subjects having a history of allergy to lidocaine and barium. * Subjects who are pregnant or lactating. * Subjects who have advanced medical disorders (e.g.: chronic obstructive pulmonary disease (COPD), congestive heart failure, cirrhosis, cancer, chronic renal failure, etc.). * Subjects who are medically unstable.
Contact & Investigator
Reza Shaker, MD
PRINCIPAL INVESTIGATOR
Medical College of Wisconsin
Frequently Asked Questions
Who can join the NCT05708911 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Dysphagia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05708911 currently recruiting?
Yes, NCT05708911 is actively recruiting participants. Contact the research team at rshaker@mcw.edu for enrollment information.
Where is the NCT05708911 trial being conducted?
This trial is being conducted at Milwaukee, United States.
Who is sponsoring the NCT05708911 clinical trial?
NCT05708911 is sponsored by Medical College of Wisconsin. The principal investigator is Reza Shaker, MD at Medical College of Wisconsin. The trial plans to enroll 60 participants.