NCT07341243 Exercising in Hot Conditions: How Does it Effect Blood Glucose in People With T1D
| NCT ID | NCT07341243 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Liverpool John Moores University |
| Condition | Type 1 Diabetes (T1D) |
| Study Type | INTERVENTIONAL |
| Enrollment | 38 participants |
| Start Date | 2025-11-01 |
| Primary Completion | 2026-11-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 38 participants in total. It began in 2025-11-01 with a primary completion date of 2026-11-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A randomised, crossover, counterbalanced repeated measures study will be conducted to examine the effect of acute heat exposure on rate of change in blood glucose concentration during 40 minutes of moderate-intensity exercise and for 30 minutes after exercise. Participants will complete two experimental conditions during two separate laboratory visits, with the order of conditions randomised. One condition will be a temperate condition of 20°C with 50% relative humidity (Temperate), the other will be 40°C with 50% relative humidity (Heat). Visits will be identical, including time of day, except for the condition. Visits will be separated by 24h. Testing will take place in the laboratories of the Research Institute for Sport and Exercise Sciences at Liverpool John Moores University.
Eligibility Criteria
Inclusion Criteria: * T1D diagnosis more than 1 years ago (to ensure participants are out of the honeymoon period) * Using insulin therapy with multiple daily injections (MDI), insulin pump (pump), or hybrid closed-loop (HCL) o If using a HCL system have experience of using a pre-programmed basal rate in manual mode during exercise * Aged 18-65 years * Regularly engaged in endurance exercise (training at least twice per week for ≥30 minutes per session) Exclusion Criteria: * Pregnancy * \<6 months postpartum or stopped breastfeeding \<1 month before recruitment * Existing cerebrovascular or cardiovascular disease * Significant history of hyperglycaemia (HbA1c \>85 mmol/mol) * History of severe hypoglycaemia requiring third party assistance within the last 3 months * Body weight \<36.5kg * Difficulty swallowing tablets * Appointment for an MRI test that cannot be rescheduled * Obstructive gastrointestinal disease * History of gastrointestinal surgery * Have an implanted medical device
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07341243 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Type 1 Diabetes (T1D). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07341243 currently recruiting?
Yes, NCT07341243 is actively recruiting participants. Contact the research team at m.s.cocks@ljmu.ac.uk for enrollment information.
Where is the NCT07341243 trial being conducted?
This trial is being conducted at Liverpool, United Kingdom.
Who is sponsoring the NCT07341243 clinical trial?
NCT07341243 is sponsored by Liverpool John Moores University. The trial plans to enroll 38 participants.
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