NCT06662955 Exercise With Audible Cues on Motor Unit Behavior in Athletes With Anterior Cruciate Ligament Reconstruction
| NCT ID | NCT06662955 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mahidol University |
| Condition | Therapeutic Exercise |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2024-10-20 |
| Primary Completion | 2026-10-19 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2024-10-20 with a primary completion date of 2026-10-19.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The closed kinetic chain (CKC) of terminal knee extension exercise (TKE) is designed to activate VM activity for knee injury training. This CKC exercise is effective for highest recruiting muscle activity, especially safe for post-operative knee surgery. The study of ACL reconstruction rehabilitation guideline suggests that exercises can be applied within the early phase of rehabilitation to prevent knee laxity and less knee pain compared to open chain exercise. Therefore, it is interesting to investigate the effects of TKE exercise synchronized with metronome pace on change of VM motor unit behavior in post operative ACL reconstruction. This study focuses on the immediate effect of 1-seesion TKE and expects that adding metronome during TKE will enhance neuromuscular control of VM and may change motor unit behavior.
Eligibility Criteria
Inclusion Criteria: * Male or female participants who receive primary ACL reconstruction within 2 weeks with or without meniscus repair * No or mild resting pain (Numeric rating scale ≤ 3) * Reconstruction procedures using autograft including hamstrings or bone-patella bone grafts * Age range 18-35 years (33). * BMI of 18.5-25 kg/m² (34). * Tegner activity scale ≥ level 4 Exclusion Criteria: * Non-weight bearing within 2 weeks after the operation (prescription from surgeon) * Hearing problem, such as being unable to hear the metronome sound or being unable to synchronize exercises with the metronome correctly * Limitations in knee extension range caused by joint stiffness evaluated by using passive knee range of motion * Unable to perform active and passive ≥ 30º knee flexion on the operative side * History of serious injury or operation of lower back and lower extremities such as fracture * Lower back or lower extremities pain within 6 months before the study * On the pain killer medication
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06662955 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 35 Years, studying Therapeutic Exercise. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06662955 currently recruiting?
Yes, NCT06662955 is actively recruiting participants. Contact the research team at komsak.sin@mahidol.edu for enrollment information.
Where is the NCT06662955 trial being conducted?
This trial is being conducted at Salaya, Thailand.
Who is sponsoring the NCT06662955 clinical trial?
NCT06662955 is sponsored by Mahidol University. The trial plans to enroll 40 participants.