NCT04812314 Exercise Effects on Adipose Tissue Structure and Function
| NCT ID | NCT04812314 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Michigan |
| Condition | Obesity |
| Study Type | INTERVENTIONAL |
| Enrollment | 46 participants |
| Start Date | 2021-03-01 |
| Primary Completion | 2028-03-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 46 participants in total. It began in 2021-03-01 with a primary completion date of 2028-03-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the weight the participant lost - followed by the same series of metabolic tests.
Eligibility Criteria
Inclusion Criteria: * Age: 18-40 * Body Mass Index: 27-45 kg/m2 * No regularly planned exercise/physical activity for at least 6 months * Women must have regularly occurring menses and must be premenopausal Exclusion Criteria: * Evidence/history of cardiovascular or metabolic disease * Medications known to affect lipid or glucose metabolism, or inflammation * Weight instability ≥ ± 6 pounds in the last 3 months * Tobacco or e-cigarette users * Women must not be pregnant or actively lactating
Contact & Investigator
Jeffrey F Horowitz, PhD
PRINCIPAL INVESTIGATOR
University of Michigan, School of Kinesiology
Frequently Asked Questions
Who can join the NCT04812314 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04812314 currently recruiting?
Yes, NCT04812314 is actively recruiting participants. Contact the research team at smlstudies@umich.edu for enrollment information.
Where is the NCT04812314 trial being conducted?
This trial is being conducted at Ann Arbor, United States.
Who is sponsoring the NCT04812314 clinical trial?
NCT04812314 is sponsored by University of Michigan. The principal investigator is Jeffrey F Horowitz, PhD at University of Michigan, School of Kinesiology. The trial plans to enroll 46 participants.
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