NCT06324422 Exercise as Treatment of Fatigue in Parkinson´s Disease
| NCT ID | NCT06324422 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Aarhus |
| Condition | Parkinson's Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 94 participants |
| Start Date | 2024-04-24 |
| Primary Completion | 2026-12-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 94 participants in total. It began in 2024-04-24 with a primary completion date of 2026-12-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary goal of this study is to test whether 12 weeks of high-intensity aerobic exercise can treat fatigue in Parkinsons disease (PD). The study will be a randomized multi-site controlled trial with follow up. Clinically fatigued persons with PD will be allocated to either 12 weeks of high-intensity aerobic exercise or to a waitlist control group receiving high-intensity resistance exercise after 24 weeks of habitual lifestyle (control period). It is hypothesized that persons with PD receiving 12 weeks of high-intensity aerobic exercise will show superior effects on perceived fatigue (i.e., clinical relevant reductions) when compared to the PD control group (primary hypothesis), and that these effects are sustained after 12-weeks of follow up (secondary hypothesis).
Eligibility Criteria
Inclusion Criteria: * Minimum 40 years * Diagnosed with Idiopathic Parkinsons disease * Stable in medical treatment for six month * Able to transport themselves to and from exercise and testing sessions (with or without assistance) * H\&Y score of three or lower Exclusion criteria: * Performing high-intensity exercise more than two times per week * Significant medical comorbidities such as cardiovascular, respiratory, orthopedic, metabolic, or other neurological disorders * Cognitive dysfunction that prevents following or understanding instructions related to training and testing (answering questionnaires) * Known depression or alcohol abuse
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06324422 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, studying Parkinson's Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06324422 currently recruiting?
Yes, NCT06324422 is actively recruiting participants. Contact the research team at ceth@ph.au.dk for enrollment information.
Where is the NCT06324422 trial being conducted?
This trial is being conducted at Aarhus, Denmark.
Who is sponsoring the NCT06324422 clinical trial?
NCT06324422 is sponsored by University of Aarhus. The trial plans to enroll 94 participants.
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