NCT07265336 Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women
| NCT ID | NCT07265336 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Saint Thomas Hospital, Panama |
| Condition | Preeclampsia |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2025-08-15 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2025-08-15 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study's primary goal is to compare the base excess (BE) values-an indicator of metabolic changes-in two groups of patients at Santo Tomás Hospital: those with severe preeclampsia and healthy, pregnant individuals. Researchers will measure these values using an arterial blood gas test before delivery or surgery. This is a prospective cohort study. The researchers will analyze various blood gas parameters, including pH, lactate, and BE, and then correlate the BE values with clinical variables and negative maternal outcomes. The expected outcome is that a abnormal BE values will be linked to a greater severity of preeclampsia. If this association is confirmed, BE could serve as an additional marker for predicting the severity of the condition and may lay the groundwork for future research on diagnostic and therapeutic standards based on blood gas analysis.
Eligibility Criteria
Inclusion Criteria: * Gestational age: 24-40 weeks * Cases: Diagnosis of severe preeclampsia * Control: Normal blood pressure Exclusion Criteria: * Metabolic conditions that could hinder the results (diabetic ketoacidosis, sepsis, renal failure). * Clinical conditions that could hinder the results (diarrhea, vomit) * Recent use of bicarbonate
Contact & Investigator
Osvaldo Reyes, MD
STUDY CHAIR
Saint Thomas Hospital, Panama
Frequently Asked Questions
Who can join the NCT07265336 clinical trial?
This trial is open to female participants only, studying Preeclampsia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07265336 currently recruiting?
Yes, NCT07265336 is actively recruiting participants. Contact the research team at fcojordan19@gmail.com for enrollment information.
Where is the NCT07265336 trial being conducted?
This trial is being conducted at Panama City, Panama.
Who is sponsoring the NCT07265336 clinical trial?
NCT07265336 is sponsored by Saint Thomas Hospital, Panama. The principal investigator is Osvaldo Reyes, MD at Saint Thomas Hospital, Panama. The trial plans to enroll 100 participants.