NCT07180498 Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction
| NCT ID | NCT07180498 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Harran University |
| Condition | Postoperative Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 54 participants |
| Start Date | 2025-04-15 |
| Primary Completion | 2025-10-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 54 participants in total. It began in 2025-04-15 with a primary completion date of 2025-10-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars. Additionally, the effects on periodontal health will be examined by comparing the gum healing processes of patients using both mouthwashes.The main questions it aims to answer are: 1. Tea tree oil, said to have anti-inflammatory and antibacterial effects, could be an alternative to chlorhexidine in reducing postoperative complications after impacted tooth extraction. 2. Does tea tree oil, which has antimicrobial effects, have as positive an impact on periodontal health as chlorhexidine?Researchers will compare tea tree oil to chlorhexidine (routinely prescribed after the extraction of an impacted wisdom tooth) to see if tea tree oil works to decrease postoperative complications. Participants will: For 7 days after the operation, they will gargle with chlorhexidine mouthwash or mouthwash containing tea tree oil 3 times a day. They will come to the clinic for check-ups and measurements on the 2nd and 7th days after the operation. They will record their pain levels and the number of painkillers they take daily.
Eligibility Criteria
Inclusion Criteria: * Individuals undergoing extraction of Class 2, Class B mandibular third molars impacted in the lower jaw (Pell \& Gregory). * Individuals aged 18-65. * Individuals must be in stable general health (e.g., free of serious cardiovascular or kidney disease). * Individuals willing to use tea tree extract or other treatments. Exclusion Criteria: * Individuals with a known allergy or hypersensitivity to tea tree extract. * Individuals with serious illnesses such as heart failure or kidney disease. Patients with bleeding disorders. * Individuals during pregnancy and breastfeeding. * Individuals taking medications that may interact with tea tree extract (e.g., blood thinners or antihypertensives) * Individuals previously treated for edema. * Individuals with chronic edema.
Contact & Investigator
Mine alkaya karagoz
PRINCIPAL INVESTIGATOR
Harran University
Frequently Asked Questions
Who can join the NCT07180498 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07180498 currently recruiting?
Yes, NCT07180498 is actively recruiting participants. Contact the research team at minekaragoz@harran.edu.tr for enrollment information.
Where is the NCT07180498 trial being conducted?
This trial is being conducted at Sanliurfa, Turkey (Türkiye).
Who is sponsoring the NCT07180498 clinical trial?
NCT07180498 is sponsored by Harran University. The principal investigator is Mine alkaya karagoz at Harran University. The trial plans to enroll 54 participants.