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Recruiting NCT05482607

NCT05482607 Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung Disease

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Clinical Trial Summary
NCT ID NCT05482607
Status Recruiting
Phase
Sponsor Central Hospital, Nancy, France
Condition Systemic Sclerosis
Study Type OBSERVATIONAL
Enrollment 100 participants
Start Date 2023-01-01
Primary Completion 2025-10-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100 participants in total. It began in 2023-01-01 with a primary completion date of 2025-10-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Systemic sclerosis (SSc) is a heterogeneous systemic autoimmune disease with distinct prognosis according to patients. Interstitial lung disease (ILD) concerns almost 50 % of SSc patients and represents the main cause of mortality. SSc-ILD is variable: from limited forms (with asymptomatic patients) to extensive lesions. Disease course in SSc-ILD is also highly variable: patients can experience stable disease, slow or fast progression. Investigators performed unsupervised clustering analysis to classify SSc-ILD according to elementary radiological lesions on HRCT scan.

Eligibility Criteria

Inclusion Criteria: * Patients with systemic sclerosis according to 2013 ACR/EULAR criteria * Patients with interstitial lung disease on HRCT chest Exclusion Criteria: * Patients with an alternative diagnosis of SSc-associated ILD (silicosis, sarcoidosis, lung cancer or other significant lung abnormalities)

Contact & Investigator

Central Contact

Paul DECKER, MD

✉ p.decker@chru-nancy.fr

📞 +33383157240

Principal Investigator

Paul Decker, MD

PRINCIPAL INVESTIGATOR

Central Hospital, Nancy, France

Frequently Asked Questions

Who can join the NCT05482607 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Systemic Sclerosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05482607 currently recruiting?

Yes, NCT05482607 is actively recruiting participants. Contact the research team at p.decker@chru-nancy.fr for enrollment information.

Where is the NCT05482607 trial being conducted?

This trial is being conducted at Nancy, France.

Who is sponsoring the NCT05482607 clinical trial?

NCT05482607 is sponsored by Central Hospital, Nancy, France. The principal investigator is Paul Decker, MD at Central Hospital, Nancy, France. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology