NCT06579547 Evaluating Replacement of Standard-of-care Low Dose Computer Tomography (CT) Scans With Radiation-free Bone Imaging by Deep-learning Augmented Zero Echo Time (DL-ZTE) Magnetic Resonance Tomography (MRT)
| NCT ID | NCT06579547 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Roman Guggenberger |
| Condition | Joint Diseases |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2024-08-01 |
| Primary Completion | 2026-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2024-08-01 with a primary completion date of 2026-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to determine how effectively bone structures of the human skeleton can be visualized using Deep Learning (DL) augmented Magnetic Resonance Imaging (MRI) in individuals with inflammatory and degenerative joint changes, compared to Computed Tomography (CT). MRI is a technique that operates without the use of X-rays. The main question it aims to answer is: 1. Can DL MRI accurately depict bone structures as well as CT? 2. Can DL MRI be used as an alternative to CT to avoid exposure to X-rays in the future? Researchers will compare DL MRI scans to CT scans to see if DL MRI can effectively replace CT in visualizing bone structures without the use of radiation. Participants will: 1. Undergo MRI scans of their skeletal system that will then be processed using DL. 2. Undergo CT scans of the same body region for comparison purposes.
Eligibility Criteria
Inclusion Criteria: * Referral for a clinically indicated MRI examination of the musculoskeletal system to assess inflammatory and degenerative joint changes. * Willingness to sign the informed consent form. * No contraindications for a CT examination (e.g., claustrophobia). Exclusion Criteria: * No signed informed consent form. * Patients under 18 years of age. * Pregnant women. * The calculated effective dose of the CT examination exceeds 5 mSv.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06579547 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Joint Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06579547 currently recruiting?
Yes, NCT06579547 is actively recruiting participants. Contact the research team at carina.obermueller@usz.ch for enrollment information.
Where is the NCT06579547 trial being conducted?
This trial is being conducted at Zurich, Switzerland.
Who is sponsoring the NCT06579547 clinical trial?
NCT06579547 is sponsored by Roman Guggenberger. The trial plans to enroll 100 participants.