| NCT ID | NCT07227727 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Craig Hospital |
| Condition | Spinal Cord Injuries |
| Study Type | OBSERVATIONAL |
| Enrollment | 40 participants |
| Start Date | 2025-07-31 |
| Primary Completion | 2027-07-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 40 participants in total. It began in 2025-07-31 with a primary completion date of 2027-07-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study plans to learn how endothelial cells, single cell lining of blood vessels may be dysfunctional after a spinal cord injury. Endothelial dysfunction will be measured by the capacity of blood vessels to vasodilate (increase in size) and alter blood flow is lower in adults with a spinal cord injury in comparison to adults without a spinal cord injury. The mechanisms which may alter this function may be critical in reducing the risk of heart attacks and strokes in people with spinal cord injuries.
Eligibility Criteria
SCI Inclusion Criteria * Over age 18 years * Chronic (\>12 months) SCI * Motor complete (AIS A/B) SCI * Paraplegia (neurological level of injury \[NLI\] at T2 or below) Non-injured Inclusion Criteria • Over age 18 years Exclusion Criteria (Both SCI and Non-injured) * Overt chronic diseases as assessed by: a) clinically documented medical history; b) physical examination; c) blood pressure and ECG at rest; and d) complete blood chemistries and hematological evaluation. * Active infection * Recent (\< 3 months) surgery * Current smoking history (within past 12 months) * Report more than low-risk alcohol consumption * History of drug abuse * Currently taking cardiovascular (statins, beta-blockers) therapeutics and/or other medications that could influence the outcome measures
Contact & Investigator
Andrew Park, MD
PRINCIPAL INVESTIGATOR
Craig Hospital
Frequently Asked Questions
Who can join the NCT07227727 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Spinal Cord Injuries. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07227727 currently recruiting?
Yes, NCT07227727 is actively recruiting participants. Contact the research team at Gmadera@craighospital.org for enrollment information.
Where is the NCT07227727 trial being conducted?
This trial is being conducted at Englewood, United States.
Who is sponsoring the NCT07227727 clinical trial?
NCT07227727 is sponsored by Craig Hospital. The principal investigator is Andrew Park, MD at Craig Hospital. The trial plans to enroll 40 participants.