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Recruiting NCT06071910

Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest

Trial Parameters

Condition Out-Of-Hospital Cardiac Arrest
Sponsor Queen Mary University of London
Study Type INTERVENTIONAL
Phase N/A
Enrollment 40
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2024-06-04
Completion 2026-06-01
Interventions
ER-REBOA catheter

Brief Summary

This study will assess the feasibility of performing pre-hospital resuscitative endovascular balloon occlusion of the aorta (REBOA) as an adjunct to conventional Advanced Life Support (ALS) in patients suffering from non-traumatic out of hospital cardiac arrest (OHCA). As well as providing valuable insights into the technical feasibility of performing this procedure as part of a resuscitation attempt, the study will also document the beneficial physiological effects of REBOA in this group of patients.

Eligibility Criteria

Inclusion criteria * Non-Traumatic OHCA in patients within the East of England area AND with a East Anglian Air Ambulance (EAAA) REBOA team in attendance * Patients below or equal to 80yrs of age and above or equal to 18yrs of age, according to available information/estimate at scene * No flow \<10 mins from data available (i.e. total period in OHCA with no CPR) * In cardiac arrest (with no sustained ROSC) on arrival of the EAAA REBOA team Exclusion criteria * Patients aged less than 18 or above 80 years * Known terminal illness * Multiple severe co-morbidities * Traumatic Cardiac Arrest (TCA) * Inability to deploy mechanical CPR (e.g. LUCAS Device) * Pregnancy, obvious or suspected

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