NCT07842536 Efficacy of Lycium Barbarum Polysaccharide in Dry Eye Disease Management
| NCT ID | NCT07842536 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Hong Kong Polytechnic University |
| Condition | Dry Eye Syndromes |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-09-14 |
| Primary Completion | 2027-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-09-14 with a primary completion date of 2027-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this pilot clinical study is to learn if Lycium barbarum polysaccharide (LBP) supplementation helps manage dry eye disease in adults. It will also learn about the safety of LBP supplementation. The main questions it aims to answer are: 1. Does LBP supplementation improve dry eye symptoms after 12 weeks? 2. Does LBP supplementation improve clinical signs of dry eye disease, such as tear film stability, tear production, and ocular surface staining? Researchers will evaluate changes in dry eye symptoms and eye examination results before and after LBP supplementation. Participants will: 1. Take LBP tablets by mouth twice daily for 12 weeks 2. Visit the clinic at baseline, 4 weeks, and 12 weeks for checkups and eye tests 3. Complete dry eye questionnaires and undergo clinical assessments of tear film, ocular surface health, and related eye measurements
Eligibility Criteria
Inclusion Criteria: * Age 18 to 60 years at enrollment. * Clinical diagnosis of dry eye disease, defined as OSDI-12 score \>=13 and at least one clinical sign of dry eye disease. * Habitual visual acuity 6/9 or better in both eyes. * Able to understand the study procedures and provide written informed consent. Exclusion Criteria: * Ocular infection within 3 months before enrollment or ocular disease other than dry eye disease. * History of ocular surgery, including refractive surgery. * Use of dry eye-related products, such as artificial tears, within 1 month before enrollment. * Contact lens wear within 1 month before enrollment. * Long-term use of medications known to affect dry eye symptoms. * Severe or unstable systemic disease. * Infectious disease, such as viral influenza. * Known allergy or hypersensitivity to Lycium barbarum polysaccharide. * Pregnant or breastfeeding. * Any condition that, in the investigator's judgment, makes the participant unsuitable for the study.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07842536 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Dry Eye Syndromes. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07842536 currently recruiting?
Yes, NCT07842536 is actively recruiting participants. Contact the research team at thomas.c.lam@polyu.edu.hk for enrollment information.
Where is the NCT07842536 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT07842536 clinical trial?
NCT07842536 is sponsored by The Hong Kong Polytechnic University. The trial plans to enroll 30 participants.