← Back to Clinical Trials
Recruiting Phase 3 NCT05055908

NCT05055908 Efficacy and Biomarker Development for Lung Cancer Treated With Immune Checkpoint Inhibitors

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05055908
Status Recruiting
Phase Phase 3
Sponsor Hunan Province Tumor Hospital
Condition Lung Cancer
Study Type INTERVENTIONAL
Enrollment 12,000 participants
Start Date 2021-10-01
Primary Completion 2025-07-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Pemetrexed plus PembrolizumabPembrolizumabPemetrexed

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 3 trials are large pivotal studies comparing the treatment to current standard of care or placebo. Your participation directly contributes to the evidence needed for regulatory approval.

This trial targets 12,000 participants in total. It began in 2021-10-01 with a primary completion date of 2025-07-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of the study is to find some biomarkers to predict the the adverse events of Immune Checkpoint Inhibitors monotherapy or plus platinum based chemotherapy in lung cancer.

Eligibility Criteria

Inclusion Criteria: 1. Understand the requirements and contents of the clinical trial, and provide a signed and dated informed consent form. 2. Age ≥ 18 years. 3. Histologically or cytologically confirmed lung cancer. 4. Treated with Immune Checkpoint Inhibitors with or without chemotherapy. 6\. Predicted survival ≥ 12 weeks. 7. Adequate bone marrow hematopoiesis and organ function 8. Presence of measurable lesions according to RECIST 1.1. Exclusion Criteria: Any conditions can not match for the Inclusion Criteria, includign do not have the data to perform Adverse Events evalutation.

Contact & Investigator

Central Contact

Yongchang Zhang, MD

✉ zhangyongchang@csu.edu.cn

📞 +8613873123436

Principal Investigator

Yongchang Zhang, MD

PRINCIPAL INVESTIGATOR

Hunan Cancer Hospital

Frequently Asked Questions

Who can join the NCT05055908 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT05055908 trial and what does that mean for participants?

Phase 3 trials are large-scale studies comparing the new treatment to existing standards of care or a placebo. They provide the evidence needed for regulatory approval. This trial targets 12,000 participants.

Is NCT05055908 currently recruiting?

Yes, NCT05055908 is actively recruiting participants. Contact the research team at zhangyongchang@csu.edu.cn for enrollment information.

Where is the NCT05055908 trial being conducted?

This trial is being conducted at Changsha, China.

Who is sponsoring the NCT05055908 clinical trial?

NCT05055908 is sponsored by Hunan Province Tumor Hospital. The principal investigator is Yongchang Zhang, MD at Hunan Cancer Hospital. The trial plans to enroll 12,000 participants.

Related Trials

Related Intelligence Guides

In-depth guides covering this condition's trials, eligibility, and what to expect.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology