NCT06295757 Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures
| NCT ID | NCT06295757 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Masonic Cancer Center, University of Minnesota |
| Condition | Tobacco Use |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2024-10-12 |
| Primary Completion | 2027-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2024-10-12 with a primary completion date of 2027-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Characterize effects of relighting on smoke toxicant deliveries and subjective smoking measures. This will be a within-subject comparison in a single experimental group of 30 smokers who report engaging in relighting behaviors. We will assess smoking intensity for relit and non-relit (i.e., smoked continuously without relighting) cigarettes in the natural environment and will conduct in-clinic measurements of smoking topography and subjective responses for relit and non-relit cigarettes. Information on relighting patterns and smoking topography collected from each participant will be used to compare machine-measured smoke yields of key harmful constituents when their usual cigarettes are smoked with and without relighting. Hypothesis: Relit cigarettes will produce higher levels of toxicants than non-relit cigarettes.
Eligibility Criteria
Inclusion Criteria: * Smoking at least 10 cigarettes/day for at least 1 year (confirmed by CO \> 8 ppm or NicAlert test of 6) * Engaging in relighting for at least half of their CPD * No smoking quit attempts in the past month nor intentions to quit in the next month * Stable medical or psychiatric conditions with systolic blood pressure \< 160, diastolic blood pressure \< 100 and heart rate \< 105 bpm Exclusion Criteria: * Participant with current or recent alcohol or drug abuse problems, use of substances of abuse (other than marijuana due to high prevalence of co-use) within the past month * Currently trying or planning to quit smoking in the next month * Planning to become pregnant, pregnant or breastfeeding. Pregnancy exclusion will be confirmed through a urine test.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06295757 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, studying Tobacco Use. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06295757 currently recruiting?
Yes, NCT06295757 is actively recruiting participants. Contact the research team at stepa011@umn.edu for enrollment information.
Where is the NCT06295757 trial being conducted?
This trial is being conducted at Minneapolis, United States.
Who is sponsoring the NCT06295757 clinical trial?
NCT06295757 is sponsored by Masonic Cancer Center, University of Minnesota. The trial plans to enroll 30 participants.