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Recruiting NCT04186416

Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients

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Trial Parameters

Condition Hypovolemia
Sponsor Assistance Publique - Hôpitaux de Paris
Study Type OBSERVATIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age N/A
Max Age 10 Years
Start Date 2023-05-03
Completion 2026-02
Interventions
Mostcare® deviceTransthoracic cardiac ultrasound

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Brief Summary

The Pressure Recording Analytical Method, invasive hemodynamic monitoring, is an uncalibrated pulse contour analysis, installed in the Mostcare® system that allows a continuous estimation of the stroke volume and thus the cardiac output, by the relationship between the area under the curve of the systolic portion of the arterial blood pressure curve and the dynamic impedance of the cardiovascular system. The objectives of the study are to determine if the parameters measured by Mostcare® make it possible to predict the response to volume expansion in pediatric surgical critical care patients, sedated, intubated and ventilated, by comparing the changes in stroke volume, induced by a volume expansion, measured by trans-thoracic echocardiography.

Eligibility Criteria

Inclusion Criteria: * Children aged 0 to 10 years old, of both sexes. * Perioperative period of surgery under general anesthesia requiring admission to surgical resuscitation (before and / or after the surgical procedure). * Patients admitted for severe trauma. * Patient installation: supine position. * Intubation and mechanical ventilation: tidal volume: 7 to 8 ml / kg, Positive expiratory pressure : 3-4 cm H2O, inspiration / expiration: 1 / 1.5 to 1/2; respiratory rate: 1 month up to 2 years = 30 / min; children 2-8 years = 20 / min; children\> 8 years = 15 / min. * Patients with arterial catheters. * Need for a volume expansion : indication given by the doctor in charge of the patient. * Non-opposition expressed by the holders of parental authority. Exclusion Criteria: * Cardiac rhythm disorders (in particular atrial fibrillation, junctional tachycardia, ventricular arrhythmias), with the exception of sinus tachycardia, respiratory variations of heart rate and sporadic atrial / vent

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