NCT07464197 Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
| NCT ID | NCT07464197 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universitat Internacional de Catalunya |
| Condition | Tooth Discoloration |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2022-05-01 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2022-05-01 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without reservoirs. Adult participants with good general and oral health and a baseline tooth shade of A2 or darker undergo bleaching with 10% carbamide peroxide. Outcomes include tooth color change (subjective and spectrophotometric measures), tooth sensitivity, gingival irritation, patient comfort, and patient satisfaction over time.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 years or older * Good general and oral health * No current medical treatment (self-reported) * No need for surgical, endodontic, periodontal, or restorative dental treatment * At least six upper and six lower anterior teeth free of caries and restorations * Maxillary central incisors with baseline shade A2 or darker * Willingness to follow the study protocol and use the study-provided oral hygiene products/instructions Exclusion Criteria: * Previous tooth bleaching treatment * Orthodontic appliances or prostheses that interfere with treatment * Severe intrinsic discoloration (e.g., tetracycline staining, fluorosis, or endodontically treated teeth with discoloration) * Pregnancy or lactation * Bruxism * Gingival recession, dentin exposure, visible enamel cracks, or other conditions associated with increased sensitivity * Use of anti-inflammatory or analgesic medication during the study period (according to protocol)
Contact & Investigator
MARTA VALLES, DDS, PhD
PRINCIPAL INVESTIGATOR
Universitat Internacional de Catalunya
Frequently Asked Questions
Who can join the NCT07464197 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Tooth Discoloration. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07464197 currently recruiting?
Yes, NCT07464197 is actively recruiting participants. Contact the research team at mvalles@uic.es for enrollment information.
Where is the NCT07464197 trial being conducted?
This trial is being conducted at Sant Cugat del Vallès, Spain.
Who is sponsoring the NCT07464197 clinical trial?
NCT07464197 is sponsored by Universitat Internacional de Catalunya. The principal investigator is MARTA VALLES, DDS, PhD at Universitat Internacional de Catalunya. The trial plans to enroll 40 participants.