NCT07295158 Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy
| NCT ID | NCT07295158 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Konya City Hospital |
| Condition | Perioperative Respiratory Mechanics |
| Study Type | INTERVENTIONAL |
| Enrollment | 138 participants |
| Start Date | 2026-03-09 |
| Primary Completion | 2026-04-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 138 participants in total. It began in 2026-03-09 with a primary completion date of 2026-04-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective laparoscopic cholecystectomy. Mechanical power will be measured at three standardized time points using a validated formula, and secondary outcomes include driving pressure values and early postoperative respiratory complications (desaturation, laryngospasm, bronchospasm, cough).
Eligibility Criteria
Inclusion Criteria: * Adults aged 18-65 years ASA Physical Status I-II Scheduled for elective laparoscopic cholecystectomy Able to provide written informed consent Exclusion Criteria: Known hypersensitivity or contraindication to study medications (sevoflurane or desflurane) Severe chronic obstructive pulmonary disease (COPD) Uncontrolled bronchial asthma Decompensated heart failure (NYHA Class III-IV) History of prior lung surgery Morbid obesity (BMI \> 35 kg/m²) Pregnancy Refusal to participate or inability to provide informed consent \-
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07295158 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Perioperative Respiratory Mechanics. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07295158 currently recruiting?
Yes, NCT07295158 is actively recruiting participants. Contact the research team at nurandr@yahoo.com for enrollment information.
Where is the NCT07295158 trial being conducted?
This trial is being conducted at Konya, Turkey (Türkiye).
Who is sponsoring the NCT07295158 clinical trial?
NCT07295158 is sponsored by Konya City Hospital. The trial plans to enroll 138 participants.