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Recruiting NCT06136039

Effect of Sarcopenia on Clinical Outcome of Total Knee Arthroplasty

Trial Parameters

Condition Knee Osteoarthritis
Sponsor Gangnam Severance Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 150
Sex FEMALE
Min Age 60 Years
Max Age N/A
Start Date 2022-06-03
Completion 2024-12-31
Interventions
Arm I (Sarcopenia)Arm II(Normal)

Brief Summary

As human life expectancy increases, the prevalence of degenerative osteoarthritis of the knee joints is steadily rising, leading to a significant surge in the frequency of total knee arthroplasty (TKA). However, research on sarcopenia in the population that comprises the primary recipients of these orthopedic joint surgeries has been notably lacking. Since the release of the 2019 Consensus update on sarcopenia by the Asian Walking Group for Sarcopenia (AWGS) in 2020, research on sarcopenia has gained momentum in various domains. Yet, as previously mentioned, the field of orthopedics still lags behind in investigating sarcopenia. Therefore, it is believed that establishing the relationship between sarcopenia and surgical outcomes in the elderly, who are the primary targets of orthopedic joint replacement surgery, could offer insights to further enhance the results of joint replacement surgeries.

Eligibility Criteria

Inclusion Criteria: * A woman aged 60 or older who is undergoing TKA due to degenerative osteoarthritis of the knee joint at the our institution. Exclusion Criteria: 1. Male 2. Under 60 years of age 3. Patients with a history of rheumatoid arthritis, traumatic joint disease, and post-infection joint disease 4. Patients who cannot undergo tests for muscle weakness diagnosis A. Patients unable to walk B. Patients unable to stand alone due to conditions like cerebral palsy or brain disorders C. Patients unable to use muscle strength 5. Patients considered inappropriate for recruitment in this study based on the judgment of the research team.

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