NCT07519057 Effect of Preoperative Oral Carbohydrate Loading on Postoperative Outcomes in Liver Transplant Patients
| NCT ID | NCT07519057 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of Warsaw |
| Condition | Liver Transplantation |
| Study Type | INTERVENTIONAL |
| Enrollment | 434 participants |
| Start Date | 2026-05-27 |
| Primary Completion | 2028-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 434 participants in total. It began in 2026-05-27 with a primary completion date of 2028-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of the study is to evaluate the effect of preoperative oral carbohydrate loading on postoperative outcomes in liver transplant recipients. The results of this study may contribute to improving recovery after liver transplantation and shortening postoperative hospital stay in these patients. Participants will be randomly assigned to either the study group or the control group. Patients assigned to the study group will receive 400 mL of a carbohydrate beverage (Nutricia preOp®), to be consumed up to 2 hours before the anesthesia induction. Patients assigned to the control group will receive 400 mL of a placebo administered in an identical manner as in the study group. Participants will not be informed which group they have been assigned to. In the postoperative period, routine laboratory and imaging tests will be performed, and their results will be used to assess the effects of the intervention. Follow-up of the patient's clinical course is planned for up to 30 days after surgery. The schedule of follow-up visits will not differ from standard clinical practice.
Eligibility Criteria
Inclusion Criteria: * age ≥ 18 years * elective liver transplantation at the Department of General, Transplant, and Liver Surgery, Medical University of Warsaw * grafts from brain-dead donors * MELD score \<35 Exclusion Criteria: * acute liver failure * insulin-dependent diabetes mellitus * gastroparesis * mechanical bowel obstruction * liver retransplantation within less than 6 months of the primary transplant
Contact & Investigator
Maciej Krasnodębski, MD, PhD
PRINCIPAL INVESTIGATOR
Department of General, Transplant, and Liver Surgery, Medical University of Warsaw
Frequently Asked Questions
Who can join the NCT07519057 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Liver Transplantation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07519057 currently recruiting?
Yes, NCT07519057 is actively recruiting participants. Contact the research team at maciej.krasnodebski@wum.edu.pl for enrollment information.
Where is the NCT07519057 trial being conducted?
This trial is being conducted at Warsaw, Poland.
Who is sponsoring the NCT07519057 clinical trial?
NCT07519057 is sponsored by Medical University of Warsaw. The principal investigator is Maciej Krasnodębski, MD, PhD at Department of General, Transplant, and Liver Surgery, Medical University of Warsaw. The trial plans to enroll 434 participants.