NCT07607795 Effect of Isometric Handgrip Exercise on Blood Pressure in Pregnant Women
| NCT ID | NCT07607795 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Poitiers |
| Condition | Pregnancy |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-03-06 |
| Primary Completion | 2027-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-03-06 with a primary completion date of 2027-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Hypertension during pregnancy is a major public health concern, increasing the risk of cardiovascular complications for both the mother and the fetus. Women with chronic hypertension are at higher risk of adverse outcomes, and elevated blood pressure during pregnancy has also been associated with long-term cardiovascular and cognitive impairments.Regular physical activity is recognized as an effective non-pharmacological strategy to reduce blood pressure. Among different exercise modalities, isometric exercise has shown promising effects in lowering blood pressure in the general population, with minimal cardiovascular strain. However, its effects and safety in pregnant women, particularly those with hypertension, remain poorly understood.In addition to cardiovascular alterations, hypertension during pregnancy may also impact cognitive function, potentially through changes in cerebral perfusion and vascular function. Despite these associations, the combined cardiovascular and cognitive responses to exercise in this population have not been fully explored.This study aims to investigate the effects of isometric handgrip exercise on cardiovascular and cognitive responses in pregnant women with and without chronic hypertension, in order to better understand its potential as a safe and effective non-pharmacological intervention during pregnancy.
Eligibility Criteria
Inclusion Criteria: * Pregnant women covered by the French National Health Insurance system * Pregnant women who do not object to participation in the study * Women belonging to one of the following two groups: * Women with chronic hypertension present before pregnancy (diagnosed within the past 5 years), defined as systolic blood pressure (SBP) ≥ 140 mmHg or diastolic blood pressure (DBP) ≥ 90 mmHg, without antihypertensive treatment * Normotensive pregnant women, defined as systolic blood pressure (SBP) \< 140 mmHg and diastolic blood pressure (DBP) \< 90 mmHg before pregnancy Exclusion Criteria: * Current treatment for chronic or gestational hypertension * Known cardiovascular disease other than chronic hypertension * Age under 18 years * Persons deprived of liberty * Inability to speak or adequately understand French * Persons hospitalized without consent who are not subject to legal protection measures, and persons admitted to a health or social institution for purposes other than research * Persons currently excluded from participation in another research study * Persons under judicial protection or guardianship Type 1 or type 2 diabetes * Severe or extreme obesity (BMI ≥ 40 kg/m²) * Thyroid disease * Heavy smoking
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07607795 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 45 Years, studying Pregnancy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07607795 currently recruiting?
Yes, NCT07607795 is actively recruiting participants. Contact the research team at carina.enea@univ-poitiers.fr for enrollment information.
Where is the NCT07607795 trial being conducted?
This trial is being conducted at Poitiers, France.
Who is sponsoring the NCT07607795 clinical trial?
NCT07607795 is sponsored by University of Poitiers. The trial plans to enroll 30 participants.