NCT07615478 Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training
| NCT ID | NCT07615478 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Macao Polytechnic University |
| Condition | Central Fatigue |
| Study Type | INTERVENTIONAL |
| Enrollment | 27 participants |
| Start Date | 2026-05-25 |
| Primary Completion | 2026-06-25 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 27 participants in total. It began in 2026-05-25 with a primary completion date of 2026-06-25.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan). Thirty adolescent athletes (aged 12-16 years) will be stratified by sex and randomly allocated to three groups: Group A (natural recovery, no immersion), Group B (38°C pure water immersion), and Group C (38°C sodium bicarbonate hot spring immersion). Interventions will be administered 3 times per week for 4 weeks. The primary outcomes are central fatigue indices including voluntary activation (VA) and central activation ratio (CAR). Secondary outcomes encompass cognitive function (Stroop test, Psychomotor Vigilance Test), cerebral hemodynamics (functional near-infrared spectroscopy, transcranial Doppler ultrasound), exercise performance (maximal oxygen uptake, 1000m test, 500m test), blood lactate, and hematological parameters (white blood cells, neutrophils, platelets).
Eligibility Criteria
Inclusion Criteria: * Male or female aged 12-16 years- Healthy with no serious chronic diseases or skin conditions * At least 1 year of systematic rowing training experience * Currently undergoing centralized altitude training at approximately 1600 meters- No history of systematic hot spring or spa immersion within the past month * No allergy history to sodium bicarbonate or hot spring minerals- Ability to provide written informed assent (participant) and written informed consent (parent/guardian)- No acute infection, fracture, or surgery within the past month * Not currently taking non-steroidal anti-inflammatory drugs (NSAIDs), immunosuppressants, or medications affecting autonomic or cognitive function Exclusion Criteria: * History of cardiovascular, respiratory, renal, endocrine, or neurological disorders- Uncontrolled hypertension or hypotension * History of syncope, heat intolerance, or severe dizziness during hot water immersion- Open wounds, severe eczema, or other skin conditions contraindicating water immersion * Current use of beta-blockers, anticholinergics, stimulants, sedatives, or other medications affecting central nervous system function * Color blindness or uncorrected visual impairment affecting Stroop test performance- Pregnancy (for female participants)- Alcohol consumption or smoking * Shift work or trans-meridian travel within 2 weeks prior to baseline assessment * Any condition deemed by the investigator as unsafe for participation
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07615478 clinical trial?
This trial is open to participants of all sexes, aged 12 Years or older, up to 16 Years, studying Central Fatigue. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07615478 currently recruiting?
Yes, NCT07615478 is actively recruiting participants. Contact the research team at p2521734@mpu.edu.mo for enrollment information.
Where is the NCT07615478 trial being conducted?
This trial is being conducted at Macao, China.
Who is sponsoring the NCT07615478 clinical trial?
NCT07615478 is sponsored by Macao Polytechnic University. The trial plans to enroll 27 participants.