NCT06561971 Effect of Different Centrifuge Values on Saliva High Sensitive C-Reactive Protein (Hs-CRP) Levels in Individuals With Different Smoking Amounts
| NCT ID | NCT06561971 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Izmir Katip Celebi University |
| Condition | Smoking |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2024-06-01 |
| Primary Completion | 2024-08-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2024-06-01 with a primary completion date of 2024-08-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study; In periodontally healthy individuals, high sensitive c-reactive protein (hs-CRP) levels of non-smokers, smokers of less than 10 cigarettes per day and smokers of more than 10 cigarettes per day were measured at 15 rpm-10 min, 10 centrifuge values, which are frequently used in saliva studies. To determine the levels in saliva samples as a result of rpm-10 min and 10 rpm 6 min centrifugations and to determine the values at which a cytokine of this molecular weight should be centrifuged and to examine the possible correlation between these values and the clinical parameters of the amount of smoking. Materials and Methods: saliva samples were collected from 90 systemically healthy individuals who were non-smokers (N, n=30), light smokers \<10 cigarettes per day (L, n=30) and heavy smokers \>10 cigarettes per day (H, n=20). samples were taken. Full-mouth clinical periodontal measurements, including probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI), and plaque index (PI), were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine hs-CRP levels in biological samples.
Eligibility Criteria
Inclusion Criteria: * Systemically healthy * Periodontally clinical healthy * At least 20 permanent teeth in the mouth * No medication for continuous use * Those who have not used antibiotics, anti-inflammatory and systemic corticosteroid drugs in the last 6 months. * Not in pregnancy or lactation period. * Not received periodontal treatment in the last 6 months * For the non-smoker group; person who does not smoke tobacco * For the light-smoker group; person who smokes less than 10 cigarettes a day * For heavy-smoker group; person who smokes more than 10 cigarettes a day Exclusion Criteria: * Any oral or systemic disease * Regularly using a systemic medication * During pregnancy or lactation * Received periodontal treatment within the last 6 months. * Those who received antibiotic, anti-inflammatory or systemic corticosteroid medication in the last 6 months * Individual with periodontal disease
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06561971 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 30 Years, studying Smoking. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06561971 currently recruiting?
Yes, NCT06561971 is actively recruiting participants. Contact the research team at ozerrece@gmail.com for enrollment information.
Where is the NCT06561971 trial being conducted?
This trial is being conducted at Izmir, Turkey (Türkiye).
Who is sponsoring the NCT06561971 clinical trial?
NCT06561971 is sponsored by Izmir Katip Celebi University. The trial plans to enroll 90 participants.