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Recruiting NCT06838013

NCT06838013 Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With Stroke

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Clinical Trial Summary
NCT ID NCT06838013
Status Recruiting
Phase
Sponsor The Hong Kong Polytechnic University
Condition Stroke
Study Type INTERVENTIONAL
Enrollment 92 participants
Start Date 2024-06-17
Primary Completion 2026-08-31

Eligibility & Interventions

Sex All sexes
Min Age 50 Years
Max Age 85 Years
Study Type INTERVENTIONAL
Interventions
Transcranial direct current stimulation (tDCS)Sham transcranial direct current stimulation (Sham-tDCS)Bilateral Transcutaneous electrical nerve stimulation (Bi-TENS)

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 92 participants in total. It began in 2024-06-17 with a primary completion date of 2026-08-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented training in people with stroke. It is hypothesize that lower limb motor function can be best improved by combining anodal tDCS with TENS, when compared with sham-tDCS with TENS, anodal tDCS with placebo-TENS, or control training at improving ankle muscle strength, motor control of lower limbs, walking performance, functional mobility and community integration in people with stroke.

Eligibility Criteria

Inclusion Criteria: 1. are between 50 and 85 years of age; 2. have had a single stroke more than 6 months and less than 15 years; 3. have at least 5 degrees of active ankle dorsiflexion in the antigravity position; 4. are able to walk 10 m independently, with or without a walking aid; 5. are able to score 6 or higher out of 10 on the abbreviated mental test; 6. have no skin allergies (e.g. redness or itchiness after application of the electrical stimulation pads) to electrical stimulation or electrodes; 7. are able to follow instructions and give informed consent. Exclusion Criteria: 1. have any additional medical, cardiovascular or orthopedic conditions that would hinder their treatment or assessment; 2. have a cardiac pacemaker; 3. have aphasia or cognitive difficulties that may interfere with their comprehension of instructions; 4. have had one or more epileptic seizures within the year prior to the date of inclusion in the study; 5. have an intracerebral metal clip; 6. have a major somatosensory deficit 7. have any contraindication to tDCS; 8. are currently involved in drug studies or other clinical trials.

Contact & Investigator

Central Contact

Shamay NG, PhD

✉ shamay.ng@polyu.edu.hk

📞 +852 27664889

Principal Investigator

Shamay Ng, PhD

PRINCIPAL INVESTIGATOR

The Hong Kong Polytechnic University

Frequently Asked Questions

Who can join the NCT06838013 clinical trial?

This trial is open to participants of all sexes, aged 50 Years or older, up to 85 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06838013 currently recruiting?

Yes, NCT06838013 is actively recruiting participants. Contact the research team at shamay.ng@polyu.edu.hk for enrollment information.

Where is the NCT06838013 trial being conducted?

This trial is being conducted at Hong Kong, Hong Kong.

Who is sponsoring the NCT06838013 clinical trial?

NCT06838013 is sponsored by The Hong Kong Polytechnic University. The principal investigator is Shamay Ng, PhD at The Hong Kong Polytechnic University. The trial plans to enroll 92 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology