NCT07627919 Effect of Combined Resisted Training and Protein-based Diet on Frailty in Sarcopenic Elderly Women
| NCT ID | NCT07627919 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cairo University |
| Condition | Obese |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2026-06-30 |
| Primary Completion | 2027-05-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2026-06-30 with a primary completion date of 2027-05-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Sixty obese elderly women will be recruited from Fawkia hospital outpatient clinic diagnosed by sarcopenia and randomly allocated into two groups for a 12-week intervention. Patients will be divided into 2 groups (A and B): * Group A (combined intervention group: n=30): will perform supervised resistance exercise training three times per week and follow a high-protein diet (1.3 g protein/kg/day) * Group B (control group: n=30): will receive a high-protein diet and general health advices and be asked to maintain their usual lifestyle. They will be offered the intervention post-study.
Eligibility Criteria
Inclusion Criteria: * 1\) Female gender 2) Age 60-70 years 3) BMI ≥ 30 kg/m2 4) Sarcopenic patients diagnosed by their physicians according to EWGSOP2 criteria (low muscle strength confirmed by handgrip strength or chair stand test, plus low muscle quantity confirmed by BIA or DXA), and SARC-F score \>3. 5\) Ambulatory and able to participate in exercise. 6) Stable medical condition. 7) The patients didn't follow any type of diet before the treatment at least 4 weeks ago. 8\) Patients didn't follow any exercise program before treatment at least 4 weeks ago. Exclusion Criteria: * 1\) Sever cardiovascular, pulmonary, renal, or hepatic disease. 2) Uncontrolled diabetes or hypertension. 3) Neurological or musculoskeletal disorders prohibiting exercise 4) Cancer or other terminal illness. 5) Current use of anti-inflammatory drugs or steroids. 6) Metal implants prohibiting BIA assessment. 7) Cognitive impairment impairing ability to consent or follow instructions. 8) Using drugs that would affect metabolism or balance. 9) Using assistive devices for walking.
Contact & Investigator
shaimaa elsayed, master
PRINCIPAL INVESTIGATOR
Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Frequently Asked Questions
Who can join the NCT07627919 clinical trial?
This trial is open to female participants only, aged 60 Years or older, up to 70 Years, studying Obese. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07627919 currently recruiting?
Yes, NCT07627919 is actively recruiting participants. Contact the research team at drshaimaaelsayed1210@gmail.com for enrollment information.
Where is the NCT07627919 trial being conducted?
This trial is being conducted at El-Sheikh Zayed City, Egypt.
Who is sponsoring the NCT07627919 clinical trial?
NCT07627919 is sponsored by Cairo University. The principal investigator is shaimaa elsayed, master at Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University. The trial plans to enroll 60 participants.