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Recruiting NCT06960304

NCT06960304 Effect of a Structured Physical Exercise Program on Arteriovenous Fistula Maturation for Hemodialysis in Chronic Kidney Disease Patients

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Clinical Trial Summary
NCT ID NCT06960304
Status Recruiting
Phase
Sponsor Unidade Local de Saúde de Coimbra, EPE
Condition Chronic Kidney Disease Requiring Hemodialysis
Study Type INTERVENTIONAL
Enrollment 128 participants
Start Date 2025-01-16
Primary Completion 2025-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Physical exercise program

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 128 participants in total. It began in 2025-01-16 with a primary completion date of 2025-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

For patients living with Chronic Kidney Disease who are preparing to start hemodialysis, having a well-functioning arteriovenous fistula (AVF) is essential. Although the AVF is considered the best type of vascular access, its maturation process does not always go as expected-studies show that in 28% to 53% of cases, the fistula does not mature properly, making effective dialysis more difficult. There is growing interest in using physical exercise as a way to support AVF maturation. International guidelines even recommend arm exercises for this purpose. However, there is still no clear agreement on what type of exercise, how often, or how intense it should be. This study aims to evaluate whether a structured exercise program focused on the AVF arm can help improve the fistula's development and overall function.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 18 years * AVF in the upper limb * No cognitive decline and ability to follow instructions Exclusion Criteria: * History of previous dysfunctional ipsilateral AVF * History of injury/condition causing pain or loss of function in the AVF limb * Musculoskeletal conditions/osteoarticular pathology (e.g., myopathy, rheumatoid arthritis) * Neurological conditions/cardiovascular events (e.g., stroke, peripheral neuropathy

Contact & Investigator

Central Contact

Ricardo A. S. Ferreira, Bachelor's degree in Nursing

✉ ricardoferreira@ulscoimbra.min-saude.pt

📞 +351 239 400 400

Principal Investigator

Ricardo A. S. Ferreira, Bachelor's degree in Nursing

PRINCIPAL INVESTIGATOR

Unidade Local de Saude de Coimbra

Frequently Asked Questions

Who can join the NCT06960304 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Chronic Kidney Disease Requiring Hemodialysis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06960304 currently recruiting?

Yes, NCT06960304 is actively recruiting participants. Contact the research team at ricardoferreira@ulscoimbra.min-saude.pt for enrollment information.

Where is the NCT06960304 trial being conducted?

This trial is being conducted at Coimbra, Portugal.

Who is sponsoring the NCT06960304 clinical trial?

NCT06960304 is sponsored by Unidade Local de Saúde de Coimbra, EPE. The principal investigator is Ricardo A. S. Ferreira, Bachelor's degree in Nursing at Unidade Local de Saude de Coimbra. The trial plans to enroll 128 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology