NCT06942494 Effect of a Family-Based CBT Self-Help Intervention for Adolescents With OCD
| NCT ID | NCT06942494 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shanghai Mental Health Center |
| Condition | Obsessive - Compulsive Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 88 participants |
| Start Date | 2025-04-30 |
| Primary Completion | 2027-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 88 participants in total. It began in 2025-04-30 with a primary completion date of 2027-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn if self-help book can be used to treat obsessive-compulsive disorder (OCD) in adolescents aged 10 to 17. The main questions it aims to answer are: Can adolescents and their parents effectively reduce the severity of the obsessive-compulsive symptoms in adolescents who are already stably taking medications through self-help books? What are the characteristics of adolescents who are best suited to use self-help intervention book to treat obsessive-compulsive symptoms? Researchers will compare the use of a self-help books plus medication with medication alone to see if the combination of the self-help intervention and drug treatment can improve the obsessive-compulsive symptoms of adolescents more effectively. Participants will: * Read one chapter of a self-help book and complete the corresponding exercise each week for 12 weeks * Visit the clinic before and after intervention for checkups and tests
Eligibility Criteria
Inclusion Criteria: 1. Age between 10 and 17 years 2. Satisfied with the diagnostic criteria for OCD in DSM-5 3. 16≤CY-BOCS score ≤23 4. Taking medication stably for 6 weeks 5. Education level ⩾6 years 6. At least one parent can accompany the patients throughout the entire intervention process 7. The patient and the participating parent have sufficient reading and writing skills to complete the treatment intervention 8. The patient and the participating parent have adequate auditory and visual abilities skills to complete the necessary examinations for the study (7) Right-handed (this criterion is for fMRI subjects only) (8) Subjects and their guardians understood the study and signed informed consent. Exclusion Criteria: 1. Obsessive-compulsive symptoms were too severe to participate in the experiment(CY-BOCS score ≥24) 2. High risk of suicide 3. Comorbid brain organic diseases, severe somatic diseases, learning disabilities, autism spectrum disorders, schizophrenia spectrum and other psychotic disorders, bipolar disorder, severe eating disorders, or substance abuse 4. Completed a Cognitive Behavioral Therapy (CBT) course for OCD within the past 12 months. 5. An IQ lower than 80 6. Currently undergoing other psychological/physical treatments 7. Uncooperative or unable to complete treatment 8. With metal implants in the body, such as pacemakers, intracranial silver clips, metal dentures, arterial stents, arterial clips, joint metal fixation, or other metal implants, etc. (this criterion is for fMRI subjects only)
Contact & Investigator
Qing Fan, Doctor
STUDY CHAIR
Shanghai Mental Health Center
Frequently Asked Questions
Who can join the NCT06942494 clinical trial?
This trial is open to participants of all sexes, aged 10 Years or older, up to 17 Years, studying Obsessive - Compulsive Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06942494 currently recruiting?
Yes, NCT06942494 is actively recruiting participants. Contact the research team at wuyiwenhsd@163.com for enrollment information.
Where is the NCT06942494 trial being conducted?
This trial is being conducted at Xuhui, China.
Who is sponsoring the NCT06942494 clinical trial?
NCT06942494 is sponsored by Shanghai Mental Health Center. The principal investigator is Qing Fan, Doctor at Shanghai Mental Health Center. The trial plans to enroll 88 participants.