NCT03255928 Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)
| NCT ID | NCT03255928 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Scientific Institute San Raffaele |
| Condition | Thrombosis |
| Study Type | OBSERVATIONAL |
| Enrollment | 60 participants |
| Start Date | 2017-06-29 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 60 participants in total. It began in 2017-06-29 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Consenting patients with end-stage heart failure that are implanted with/candidates for implant of a short-term/durable mechanical circulatory support device (e.g.: percutaneous microaxial pumps (Impella), extracorporeal membrane oxygenator (ECMO), Ventricular Assist Device (VAD) will be enrolled in the study. Aim of the study is to evaluate the patients' haemostatic and coagulation profile, how it interacts with the support device as well as the effect of antithrombotic drugs. From these data, it will be possible to derive the mechanisms triggering post-implant thromboembolic/hemorrhagic complications and to identify potential therapeutic targets.
Eligibility Criteria
Inclusion Criteria: * All consenting patients candidates for short-term (Impella, ECMO) or durable (LVAD) mechanical circulatory support device implantation * All consenting patients that are implanted with short-term (Impella, ECMO) or durable (LVAD) mechanical circulatory support device Exclusion Criteria: \- Patients \< 18-years old
Contact & Investigator
Filippo Consolo, PhD
PRINCIPAL INVESTIGATOR
San Raffaele Scientific Institute
Frequently Asked Questions
Who can join the NCT03255928 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Thrombosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03255928 currently recruiting?
Yes, NCT03255928 is actively recruiting participants. Contact the research team at consolo.filippo@unisr.it for enrollment information.
Where is the NCT03255928 trial being conducted?
This trial is being conducted at Milan, Italy.
Who is sponsoring the NCT03255928 clinical trial?
NCT03255928 is sponsored by Scientific Institute San Raffaele. The principal investigator is Filippo Consolo, PhD at San Raffaele Scientific Institute. The trial plans to enroll 60 participants.