NCT07092943 Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries
| NCT ID | NCT07092943 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Rawalpindi Medical College |
| Condition | Mechanical Ventilation |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2025-07-20 |
| Primary Completion | 2025-10-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2025-07-20 with a primary completion date of 2025-10-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patient undergoing surgeries in general anesthesia require support of their breathing by ventilator. Different strategies can be used to manage breathing of the patient. Lung protective ventilation provides breathing at a set volume determined by patient ideal body weight, along with a set rate to maintain adequate breathing. The pressures in the lower airway are kept less than 30 cm of H20 while a pressure of 5cm of H20 is applied to prevent lung collapse. Recently to above mentioned regimen a driving pressure is added which is a difference between lower airway pressure and pressure applied to prevent lung collapse. Ventilatory settings are adjusted to keep this driving pressure less than 15 cm of H2O.
Eligibility Criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) class: I and II. * Elective laparoscopic surgeries requiring General Anesthesia and Mechanical ventilation * Patients receiving neuromuscular blockade during surgery. * Receiving Mechanical ventilation for at least 1h. Exclusion Criteria: * Pregnancy * Patients who had received mechanical ventilation of more than 1h in the previous 2 weeks. * Body mass index \>35 kg/m2 * Smokers and ASA class III and above. * Thoracic and Cardiac surgery
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07092943 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, up to 80 Years, studying Mechanical Ventilation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07092943 currently recruiting?
Yes, NCT07092943 is actively recruiting participants. Contact the research team at Huda8829@gmail.com for enrollment information.
Where is the NCT07092943 trial being conducted?
This trial is being conducted at Rawalpindi, Pakistan.
Who is sponsoring the NCT07092943 clinical trial?
NCT07092943 is sponsored by Rawalpindi Medical College. The trial plans to enroll 70 participants.