NCT04122456 DNA Repair Activity in the Skin of Day and Night Shift Workers
| NCT ID | NCT04122456 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Wright State University |
| Condition | Skin Cancer |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2022-12-07 |
| Primary Completion | 2025-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2022-12-07 with a primary completion date of 2025-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to test how the skin of night shift workers responds to artificial sunlight (ultraviolet B radiation; UVB) at two different times of the day in comparison to normal day shift workers. After the skin biopsies are obtained, they will be brought to the laboratory to be exposed to UVB radiation and to measure UVB responses.
Eligibility Criteria
Inclusion Criteria: * Male/Female * Fair skin (Fitzpatrick types I and II) * Age 18 to 40 * Able to comprehend procedures/risks * Primarily work and are awake during normal daylight hours (6 am to 6 pm), or primarily work and are awake during night shifts hours (between the hours of 6 pm and 6 am) or may work a mixture of these shifts over the past 3 months. Rotating shifts will be categorized based on the majority of hours worked on average during the last 3 months. Able to fill out a 3-month calendar of work schedule. Exclusion Criteria: * Known photosensitivity * Currently on photosensitizing medications * Diabetes Mellitus * On any hormonal agents (e.g., birth control pills) * History of abnormal scarring * History of skin infections * History of skin cancers * History of sleep disorders such as sleep apnea or insomnia * Known allergy to lidocaine local anesthetic * Pregnancy or nursing * Other serious health issues
Contact & Investigator
Jeffrey B Travers, MD, PhD
PRINCIPAL INVESTIGATOR
Wright State University
Frequently Asked Questions
Who can join the NCT04122456 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Skin Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04122456 currently recruiting?
Yes, NCT04122456 is actively recruiting participants. Contact the research team at pturesearch@wrightstatephysicians.org for enrollment information.
Where is the NCT04122456 trial being conducted?
This trial is being conducted at Fairborn, United States.
Who is sponsoring the NCT04122456 clinical trial?
NCT04122456 is sponsored by Wright State University. The principal investigator is Jeffrey B Travers, MD, PhD at Wright State University. The trial plans to enroll 48 participants.
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