NCT07348510 Diuretic Effect of Aminophylline and Furosemide in Adult Patients Undergoing Cardiac Surgical Procedures
| NCT ID | NCT07348510 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cairo University |
| Condition | Diuretic Effect |
| Study Type | INTERVENTIONAL |
| Enrollment | 106 participants |
| Start Date | 2026-01-17 |
| Primary Completion | 2026-07-26 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 106 participants in total. It began in 2026-01-17 with a primary completion date of 2026-07-26.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This work aims to investigate the diuretic effect of Aminophylline in comparison to Furosemide in adult patients undergoing cardiac surgical procedures.
Eligibility Criteria
Inclusion Criteria: * Age from 18-65 years. * Both sexes. * All adult patients presenting for elective cardiac surgical procedures performed on cardiopulmonary bypass (Coronary artery bypass surgery, Cardiac valve repair and/or replacement, Repair of large septal defects, Repair and/or palliation of congenital heart defects, Transplantation, surgery of thoracic aneurysms.). * Body mass index (BMI) ranged between 20 and 40 kg/m2. Exclusion Criteria: * Sensitivity or contraindication to Aminophylline or furosemide * Stage-5 chronic kidney disease (CKD) \[Glomerular filtration rate (GFR) of less than 15 mL/min\]. * The presence of both factors (GFR less than 60 mL/min and albumin greater than 30 mg per gram of creatinine) along with abnormalities of kidney structure or function for greater than three months signifies chronic kidney disease. * Recipients of dialysis before surgery. * Recipients of solid-organ transplantation before surgery. * Emergency cardiac surgical procedures (e.g. left main coronary artery bypass graft, stuck valves, etc). * Patient refusal.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07348510 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Diuretic Effect. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07348510 currently recruiting?
Yes, NCT07348510 is actively recruiting participants. Contact the research team at ahm33hassan@gmail.com for enrollment information.
Where is the NCT07348510 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT07348510 clinical trial?
NCT07348510 is sponsored by Cairo University. The trial plans to enroll 106 participants.