NCT06582316 Digital Solution for Salutogenic Brain Health (DiSaB): A Pilot Protocol for Clinical Implementation
| NCT ID | NCT06582316 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National University of Singapore |
| Condition | Chronic Condition |
| Study Type | INTERVENTIONAL |
| Enrollment | 160 participants |
| Start Date | 2025-04-02 |
| Primary Completion | 2026-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 160 participants in total. It began in 2025-04-02 with a primary completion date of 2026-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to develop and learn if a digitally delivered brain health intervention (DiSaB) can help improve cognitive, physical and psychosocial health in middle-aged adults with chronic conditions at-risk for cognitive decline. The clinical trial also aims to find out the push and pull factors of implementing the intervention in primary care settings. The main questions it aims to answer are: 1. Does the DiSaB intervention improve participants' cognitive functions, health measures, and psychosocial health? 2. Is an individualised or group-based health education session better at improving cognitive, physical and psychosocial health in participants who did not respond to the DiSaB intervention? 3. How useful and practical is the DiSaB intervention, according to 1. participants and 2. nurses carrying out the intervention? The investigators will compare a DiSaB intervention to a control condition (where participants do not undergo any intervention) to see if the DiSaB intervention works in improving participants' health. The investigators will also compare individualised versus group health education sessions to see which session is better at improving the health of participants who did not respond to the DiSaB intervention. Participants will 1. Complete cognitive assessments, questionnaires, and health tests before intervention, immediately after the intervention, and 6 months after the intervention 2. Either undergo no intervention, or undergo the DiSaB intervention over 2 months 3. Be randomly selected to attend focus group interviews Local champions will complete questionnaires and attend focus group interviews after administering and/or co-facilitating the intervention.
Eligibility Criteria
Inclusion Criteria: * Aged 40 - 55 years old * Have hypertension, hyperlipidaemia and/or type-2 diabetes * Ability to provide written informed consent * Posses sufficient English language skills in reading, writing and speaking * Multimorbidity conditions are also acceptable with the exception of life-threatening co-morbidities with life expectancy of less than one year * Total Risk Score (TRS) for cognitive impairment of at least 3 Exclusion Criteria: * Physical, visual and/or hearing impairment * Language impairment (i.e. severe dysarthria or aphasia) * Not within age range listed * Major or active psychiatric conditions * Diagnosis of dementia * Do not own a mobile device capable of downloading applications (i.e. Zoom), and/or do not have access to internet connection
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06582316 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, up to 64 Years, studying Chronic Condition. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06582316 currently recruiting?
Yes, NCT06582316 is actively recruiting participants. Contact the research team at nurdy@nus.edu.sg for enrollment information.
Where is the NCT06582316 trial being conducted?
This trial is being conducted at Singapore, Singapore.
Who is sponsoring the NCT06582316 clinical trial?
NCT06582316 is sponsored by National University of Singapore. The trial plans to enroll 160 participants.