NCT07903792 Diagnostic Value of Oropharyngeal Suction and Effect of Respiratory Physiotherapy on the Detection of Microorganisms in the Pediatric Patient
| NCT ID | NCT07903792 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Corporacion Parc Tauli |
| Condition | Cystic Fibrosis (CF) |
| Study Type | INTERVENTIONAL |
| Enrollment | 196 participants |
| Start Date | 2026-06-01 |
| Primary Completion | 2028-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 196 participants in total. It began in 2026-06-01 with a primary completion date of 2028-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to determine the effectiveness of oropharyngeal suction in detecting microorganisms by comparing it with induced sputum and oropharyngeal swab samples. It also aims to assess the effect of respiratory physiotherapy on improving the results obtained in children aged 5-18 years with chronic lung disease. The main questions it aims to answer are: * What is the diagnostic efficacy of oropharyngeal suction in detecting microorganisms compared with induced sputum? * What is the effect of undergoing a physiotherapy session before sample collection? * How do the results obtained from oropharyngeal suction correlate with those obtained from oropharyngeal swabs? * How does the age of the participants affect the results obtained from each sampling technique and the effect of prior physiotherapy? * Are these techniques safe? Researchers will compare samples collected after a physiotherapy session with those collected without prior physiotherapy to determine whether physiotherapy improves culture results. Participants will be randomized into two groups: one group will undergo a physiotherapy session before sample collection, while the other will not. Three samples will be collected from each participant using oropharyngeal suction, an oropharyngeal swab, and induced sputum. Each participant may take part on multiple occasions, provided that at least one month has elapsed since their previous participation. On each occasion, participants will be randomized again.
Eligibility Criteria
Inclusion Criteria: * Having a chronic respiratory disease that requires sputum sample collection. * Being able to cooperate during the physiotherapy session. * Having provided signed informed consent. Exclusion Criteria: * Severe acute infection that contraindicates any of the procedures (e.g., severe respiratory failure, shock, etc.). * Having taken antibiotics in the previous week, except for patients receiving chronic azithromycin treatment. * Decompensated cardiorespiratory disease. * History of severe adverse reactions to hypertonic saline nebulization. * Patients who do not consent to or are unable to undergo the procedures.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07903792 clinical trial?
This trial is open to participants of all sexes, aged 5 Years or older, up to 18 Years, studying Cystic Fibrosis (CF). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07903792 currently recruiting?
Yes, NCT07903792 is actively recruiting participants. Contact the research team at avallsl@tauli.cat for enrollment information.
Where is the NCT07903792 trial being conducted?
This trial is being conducted at Sabadell, Spain.
Who is sponsoring the NCT07903792 clinical trial?
NCT07903792 is sponsored by Corporacion Parc Tauli. The trial plans to enroll 196 participants.