NCT06395415 Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults
| NCT ID | NCT06395415 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Chicago |
| Condition | Electronic Nicotine Delivery Systems |
| Study Type | INTERVENTIONAL |
| Enrollment | 46 participants |
| Start Date | 2025-04-25 |
| Primary Completion | 2026-07 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 46 participants in total. It began in 2025-04-25 with a primary completion date of 2026-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Electronic Nicotine Delivery Systems (ENDS) use remains prevalent among young adults, and many have high interest in quitting, yet research on effective intervention is lacking. A mobile health (mHealth) intervention that translates effective smoking cessation materials and pharmacotherapy may be a promising avenue for intervention. The initial phase of the proposed study uses a pilot study to evaluate a novel mHealth intervention for young adult ENDS and dual product (ENDS and combustible cigarette) users.
Eligibility Criteria
Inclusion Criteria: 1. Age 18-26 years old, ability to understand the English language, willing and able to provide informed consent 2. Current ENDS user (at least 4 out of 7 days per week of use for the past one month); for focus groups, at least half of participants will report current cigarette smoking (at least 1 cigarette per day on at least 1 day per week in the past month) 3. Report interest in quitting or reducing ENDS (at least 6/10 scale in interest of quitting or reducing 4. Does not currently (in past one year) meet criteria for major psychiatric disorder including severe alcohol or substance use disorder (excluding tobacco use disorder), schizophrenia, bipolar disorder, and obsessive compulsive disorder 5. For women, not currently pregnant, planning to become pregnant, or breastfeeding due to lack of information on ENDS use and possible harms from NRT during pregnancy 6. Not currently using smoking cessation medication (i.e., Varenicline, Bupropion 7. No history of adverse reactions to nicotine replacement therapy Exclusion Criteria: 1. Does not own a mobile phone or is unwilling to receive text messages to their device 2. No interest in quitting or reducing use of ENDS 3. Uses electronic cigarettes less than 4 days per week in the past month 4. Reports past-year serious psychiatric illness, including severe alcohol or substance use disorder (excluding tobacco use disorder), schizophrenia, bipolar disorder, and obsessive compulsive disorder 5. Is currently using smoking cessation medication including Varenicline or Bupropion 6. Are a female who is currently pregnant or nursing or planning to become pregnant within the next 6 months
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06395415 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 26 Years, studying Electronic Nicotine Delivery Systems. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06395415 currently recruiting?
Yes, NCT06395415 is actively recruiting participants. Contact the research team at ebrett@bsd.uchicago.edu for enrollment information.
Where is the NCT06395415 trial being conducted?
This trial is being conducted at Chicago, United States.
Who is sponsoring the NCT06395415 clinical trial?
NCT06395415 is sponsored by University of Chicago. The trial plans to enroll 46 participants.