NCT07333560 Development and Pre-validation of a Machine Learning-based Prediction Algorithm for Early Functional Recovery in Patients Undergoing Hip and Knee Replacement Surgery
| NCT ID | NCT07333560 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Istituto Ortopedico Rizzoli |
| Condition | Artificial Intelligence (AI) |
| Study Type | OBSERVATIONAL |
| Enrollment | 943 participants |
| Start Date | 2026-03-09 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 943 participants in total. It began in 2026-03-09 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to develop and pre-validate a machine learning algorithm to predict early recovery of mobility in patients undergoing hip or knee joint replacement surgery. The primary research question is: Can a machine learning model accurately classify patients with faster versus slower recovery of autonomous mobility in the first days after joint replacement surgery? Patients who have undergone elective hip or knee arthroplasty and received post-operative physiotherapy will have their clinical and perioperative data collected retrospectively (2020-2023) and prospectively (March 2026-December 2027). The algorithm will be trained on retrospective data and tested prospectively to evaluate its predictive performance for early mobilization and length of hospital stay.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 years or older * Patients underwent elective hip or knee arthroplasty. * Patients for whom postoperative physiotherapy was initiated. Exclusion Criteria: * Patients who underwent surgery for oncologic disease, femoral fracture, or revision joint arthroplasty. * Patients for whom postoperative physiotherapy was not provided due to postoperative complications * clinical data are unavailable.
Contact & Investigator
Mattia Morri
PRINCIPAL INVESTIGATOR
IRCCS Istotuto Ortopedico Rizzoli
Frequently Asked Questions
Who can join the NCT07333560 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Artificial Intelligence (AI). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07333560 currently recruiting?
Yes, NCT07333560 is actively recruiting participants. Contact the research team at mattia.morri@ior.it for enrollment information.
Where is the NCT07333560 trial being conducted?
This trial is being conducted at Bologna, Italy, Reggio Emilia, Italy.
Who is sponsoring the NCT07333560 clinical trial?
NCT07333560 is sponsored by Istituto Ortopedico Rizzoli. The principal investigator is Mattia Morri at IRCCS Istotuto Ortopedico Rizzoli. The trial plans to enroll 943 participants.