NCT07340242 Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
| NCT ID | NCT07340242 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mansoura University |
| Condition | Class II Malocclusion |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2025-04-27 |
| Primary Completion | 2026-10-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2025-04-27 with a primary completion date of 2026-10-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is considered one of the most commonly observed problems among orthodontic patients, representing around one-third of the patients seeking orthodontic treatment reflecting a significant economic impact. Various removable and fixed functional appliances are commonly used to stimulate mandibular growth. Fixed Twin-block appliance has advantages compared with removable Twin-block and Herbst appliances. The mandibular anterior repositioning appliance is referred to as M.A.R.A. appliance. Materials and method: The study design is a randomized controlled trial in which the control group and intervention groups will be assessed as parallel groups with a 1:1:1 allocation ratio. Sixty subjects will be enrolled in this research. They will be divided equally into three groups: untreated control, MARA group and Twin block group
Eligibility Criteria
Inclusion Criteria: 1. Skeletal Class II malocclusion due to mandibular retrusion. 2. Overjet ≥ 6.0 mm. 3. Normal or low-angle growth pattern. 4. Minimum crowding in the mandibular arch. 5. Undergoing circumpubertal phase of skeletal development (CVMI 2, 3, and 4) Exclusion Criteria: 1. Clinical signs and symptoms of temporomandibular disorder. 2. Systemic disease affecting bone and general growth. 3. Previous orthodontic treatment 4. Cleft lip or palate. 5. Congenital craniofacial deformity. 6. Abnormal oral habits.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07340242 clinical trial?
This trial is open to participants of all sexes, aged 9 Years or older, up to 14 Years, studying Class II Malocclusion. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07340242 currently recruiting?
Yes, NCT07340242 is actively recruiting participants. Contact the research team at yasminghaly@mans.edu.eg for enrollment information.
Where is the NCT07340242 trial being conducted?
This trial is being conducted at Al Mansurah, Egypt.
Who is sponsoring the NCT07340242 clinical trial?
NCT07340242 is sponsored by Mansoura University. The trial plans to enroll 60 participants.