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Recruiting NCT07122713

NCT07122713 Definitive Radiation Therapy for Inoperable Breast Cancer

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Clinical Trial Summary
NCT ID NCT07122713
Status Recruiting
Phase
Sponsor Alexander Stessin
Condition Breast Cancer
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2025-12-08
Primary Completion 2028-12-30

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Whole breast radiation with simultaneous integrated boost (WB-SIB) to primary breast tumorWhole breast radiation with simultaneous integrated boost (WB-SIB) to primary breast tumor and ipsilateral axillary lymph nodes

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 30 participants in total. It began in 2025-12-08 with a primary completion date of 2028-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to find out if adding radiation therapy to routine medications for breast cancer helps in reducing and preventing the cancer from getting worse. Patients with a locally advanced breast cancer who cannot, or do not want to, undergo surgery are eligible to participate. Participation in this study does not prevent you from undergoing surgery in the future.

Eligibility Criteria

Inclusion Criteria: * Biopsy proven invasive carcinoma of the breast, either lobular, ductal and/or no special type * T1-T4, N0-2, M0-1 invasive breast carcinoma by radiological or clinical criteria * Cancer is deemed unresectable, or the patient is a poor surgical candidate as determined following evaluation by a surgeon, or patient declines surgery. * Life expectancy \> 6 months * Negative pregnancy test at the time of start of treatment in any female of reproductive age Exclusion Criteria: * Concurrent systemic therapy (except for endocrine therapy, HER2-targeted therapy, or immunotherapy which are permitted) * Prior radiation to ipsilateral breast or regional nodes * Inability to receive study treatment planning and treatment secondary to body habitus

Contact & Investigator

Central Contact

Caterina Stony Brook Cancer Center Clinical Trials

✉ cancerclinicaltrials@sronybrookmedicine.edu

📞 631-728-7425

Principal Investigator

Alexander Stessin, MD PhD

PRINCIPAL INVESTIGATOR

Stony Brook University Hospital

Frequently Asked Questions

Who can join the NCT07122713 clinical trial?

This trial is open to female participants only, aged 18 Years or older, studying Breast Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07122713 currently recruiting?

Yes, NCT07122713 is actively recruiting participants. Contact the research team at cancerclinicaltrials@sronybrookmedicine.edu for enrollment information.

Where is the NCT07122713 trial being conducted?

This trial is being conducted at Stony Brook, United States.

Who is sponsoring the NCT07122713 clinical trial?

NCT07122713 is sponsored by Alexander Stessin. The principal investigator is Alexander Stessin, MD PhD at Stony Brook University Hospital. The trial plans to enroll 30 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology