NCT05371977 Deep Sclerectomy Versus Trabeculectomy in Normal Tension Glaucoma
| NCT ID | NCT05371977 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Helsinki University Central Hospital |
| Condition | Normal Tension Glaucoma |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2022-05-31 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2022-05-31 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to assess whether deep sclerectomy is as effective in lowering intraocular pressure (IOP) as trabeculectomy in patients with normal tension glaucoma.
Eligibility Criteria
Inclusion Criteria: * Signed Informed Consent * Normal Tension Glaucoma with typical nerve fiber layer defects in red-free photographs and/or optical coherence tomography (OCT) and possible equivalent visual field defects, IOP never more than 21 mmHg, and open anterior chamber angle * Glaucoma unstable with current medication assessed by a glaucoma specialist Exclusion Criteria: * Secondary Glaucoma e.g. due to previous injury or uveitis * Exfoliation syndrome * Pigment dispersion syndrome * Previous transscleral or endoscopic cyclophotocoagulation * Previous other glaucoma surgery * Previous retinal detachment * Previous intraocular surgery like vitrectomy and other retinal surgery * Wet age-related macular degeneration * Diabetic retonopathy * Previous corneal transplant or previous refractive surgery * Fuchs' dystrophy and other abnormalities compromising corneal clarity like scars * The patient does not want to participate in the study * The patient does not speak Finnish, Swedish or English * Dementia * Only eye with vision worse than 20/200 or loss of central visual field
Frequently Asked Questions
Who can join the NCT05371977 clinical trial?
This trial is open to participants of all sexes, aged 55 Years or older, up to 100 Years, studying Normal Tension Glaucoma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05371977 currently recruiting?
Yes, NCT05371977 is actively recruiting participants. Visit ClinicalTrials.gov or contact Helsinki University Central Hospital to inquire about joining.
Where is the NCT05371977 trial being conducted?
This trial is being conducted at Helsinki, Finland.
Who is sponsoring the NCT05371977 clinical trial?
NCT05371977 is sponsored by Helsinki University Central Hospital. The trial plans to enroll 80 participants.