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Recruiting NCT05371977

Deep Sclerectomy Versus Trabeculectomy in Normal Tension Glaucoma

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Trial Parameters

Condition Normal Tension Glaucoma
Sponsor Helsinki University Central Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 80
Sex ALL
Min Age 55 Years
Max Age 100 Years
Start Date 2022-05-31
Completion 2026-05
Interventions
TrabeculectomyDeep Sclerectomy

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Brief Summary

The purpose of this study is to assess whether deep sclerectomy is as effective in lowering intraocular pressure (IOP) as trabeculectomy in patients with normal tension glaucoma.

Eligibility Criteria

Inclusion Criteria: * Signed Informed Consent * Normal Tension Glaucoma with typical nerve fiber layer defects in red-free photographs and/or optical coherence tomography (OCT) and possible equivalent visual field defects, IOP never more than 21 mmHg, and open anterior chamber angle * Glaucoma unstable with current medication assessed by a glaucoma specialist Exclusion Criteria: * Secondary Glaucoma e.g. due to previous injury or uveitis * Exfoliation syndrome * Pigment dispersion syndrome * Previous transscleral or endoscopic cyclophotocoagulation * Previous other glaucoma surgery * Previous retinal detachment * Previous intraocular surgery like vitrectomy and other retinal surgery * Wet age-related macular degeneration * Diabetic retonopathy * Previous corneal transplant or previous refractive surgery * Fuchs' dystrophy and other abnormalities compromising corneal clarity like scars * The patient does not want to participate in the study * The patient does not speak Finnish, Swedish

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