NCT07387107 Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults
| NCT ID | NCT07387107 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Heart and Brain Research Group, Germany |
| Condition | Stress |
| Study Type | INTERVENTIONAL |
| Enrollment | 52 participants |
| Start Date | 2026-03-05 |
| Primary Completion | 2026-07-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 52 participants in total. It began in 2026-03-05 with a primary completion date of 2026-07-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is a non-clinical substudy conducted within the DESTRESS research program (NCT05036538), which investigates the effects of relaxation interventions on physiological and psychological parameters. While the main DESTRESS trial focuses on cardiac surgical patients, this additional study arm examines the same interventions in a non-clinical adult population under controlled conditions, independent of disease-, surgery-, or medication-related influences. Participants are randomly assigned to one of several experimental conditions and take part in a single approximately 30-minute session. Depending on group allocation, the session may include exposure to natural soundscapes, natural soundscapes combined with binaural beats, virtual reality-based natural environments, virtual reality combined with binaural beats, or a control condition without a relaxation intervention. The primary aim of the DESTUD-Study is to assess the feasibility and potential stress-reducing effects of these non-pharmacological relaxation approaches in a non-clinical setting and to support the interpretation of findings from the clinical DESTRESS trial. Physiological responses, including heart rate variability and electrodermal activity, as well as self-reported stress measures, are collected before, during and after the conditions.
Eligibility Criteria
Inclusion Criteria: 1\. Adults aged 18 years or older 2. Ability to understand study procedures and provide written informed consent 3. Sufficient proficiency in the German language to complete questionnaires and follow study instructions 4. Willingness to participate in a single approximately 60-minute study session Exclusion Criteria: 1\. Current or history of neurological or psychiatric disorders that may interfere with data collection (e.g., dementia, major depressive disorder, stroke, epilepsy) 2. Severe visual or hearing impairments that would limit the use of virtual reality equipment or headphones 3. History of adverse reactions to virtual reality
Contact & Investigator
Marius Butz, PhD, M.Sc.
PRINCIPAL INVESTIGATOR
Heart&Brain Research Group, Kerckhoff-Clinic, Bad Nauheim, Germany
Frequently Asked Questions
Who can join the NCT07387107 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Stress. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07387107 currently recruiting?
Yes, NCT07387107 is actively recruiting participants. Contact the research team at m.butz@kerckhoff-klinik.de for enrollment information.
Where is the NCT07387107 trial being conducted?
This trial is being conducted at Bad Nauheim, Germany.
Who is sponsoring the NCT07387107 clinical trial?
NCT07387107 is sponsored by Heart and Brain Research Group, Germany. The principal investigator is Marius Butz, PhD, M.Sc. at Heart&Brain Research Group, Kerckhoff-Clinic, Bad Nauheim, Germany. The trial plans to enroll 52 participants.