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Recruiting NCT05305482

DCS Versus DES for One-month DAPT in Patients With ACS: ONE-PASS Trial

Trial Parameters

Condition Acute Coronary Syndrome
Sponsor Yonsei University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 3,520
Sex ALL
Min Age 19 Years
Max Age N/A
Start Date 2022-08-10
Completion 2030-02-14
Interventions
Drug-coated stentDrug-eluting stent

Brief Summary

To test whether the polymer-free drug-coated stent (DCS) BioFreedom is noninferior to the biodegradable polymer drug-eluting stent (DES) Ultimaster in terms of 1-year patient-oriented composite endpoint (POCE, composite of all-cause mortality, any MI, or any revascularization) in a setting of 1-month dual-antiplatelet therapy (DAPT) strategy (1-month DAPT followed ticagrelor monotherapy) after acute coronary syndrome.

Eligibility Criteria

Inclusion Criteria: 1. Age ≥19 years 2. All subjects who are acceptable candidates for treatment with a drug-coated stent or drug-eluting stent because of acute coronary syndrome 3. Provision of informed consent Exclusion Criteria: 1. Current or potential pregnancy 2. Need of oral anticoagulation therapy 3. Inability to follow the patient over the period of 1 year after enrollment, as assessed by the investigator

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