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Recruiting NCT06455995

NCT06455995 Daily Eating Patterns for Total Health Study

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Clinical Trial Summary
NCT ID NCT06455995
Status Recruiting
Phase
Sponsor The University of Tennessee, Knoxville
Condition Obesity
Study Type INTERVENTIONAL
Enrollment 174 participants
Start Date 2024-07-16
Primary Completion 2028-12

Eligibility & Interventions

Sex All sexes
Min Age 25 Years
Max Age 60 Years
Study Type INTERVENTIONAL
Interventions
DEPTHDEPTH-MorningDEPTH-Evening

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 174 participants in total. It began in 2024-07-16 with a primary completion date of 2028-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this randomized controlled trial is to learn how the time of day when calories are eaten affects weight loss in the long-term (12 months). The main aims are to learn: 1. The influence of time-based energy intake goals on longer-term weight loss. 2. The influence of time-based energy intake goals on eating temporal patterns, sleep regularity, and appetite regulation. Researchers will compare whether goals to eat most of a person's calories in the morning or evening work to treat obesity. Participants will: 1. Eat a reduced-calorie, low-fat diet (some participants will have goals to eat their calories at certain times of day based on their group) 2. Be physically active at least 200 minutes 3. Receive a cognitive behavioral intervention

Eligibility Criteria

Inclusion Criteria: * Body mass index (BMI) between 27 and 45 kg/m2. Exclusion Criteria: * Report not regularly (\>/= 5 days/wk) consuming energy (\>/= 100 kcal) prior to 12 pm, and not being able to consume energy every day (\>/= 50 kcal) within one hour of awakening. * Report taking sleep medication or not regularly (\>/= 5 nights/wk) getting at least 6 hrs of total sleep. * Report being a shift workers/alternative shift workers that work outside of 7 am and 7 pm. * Report being diagnosed with type 1, or type 2 diabetes and taking medication that requires eating to occur at certain time periods. * Report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q). Individuals reporting joint problems, prescription medication usage, or other medical conditions that could limit exercise will be required to obtain written physician consent to participate. * Report being unable to walk for 2 blocks (1/4 mile) without stopping. * Report major psychiatric diseases or organic brain syndromes. * Report currently participating in a weight loss program and/or taking weight loss or appetite regulation medication or lost \>/= 5% of body weight during the past 6 months. * Report having bariatric surgery for weight loss/planning to have bariatric surgery in the next 12 months. * Report being pregnant, lactating, \< 6 months post-partum or plan to become pregnant (next 12 months). * Report planning to move outside of the metropolitan area within the time frame of the investigation. * Do not have daily access to PC with internet or smartphones (needed for self-monitoring).

Contact & Investigator

Central Contact

Hollie A Raynor, PhD

✉ hraynor@utk.edu

📞 865-974-9126

Frequently Asked Questions

Who can join the NCT06455995 clinical trial?

This trial is open to participants of all sexes, aged 25 Years or older, up to 60 Years, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06455995 currently recruiting?

Yes, NCT06455995 is actively recruiting participants. Contact the research team at hraynor@utk.edu for enrollment information.

Where is the NCT06455995 trial being conducted?

This trial is being conducted at Knoxville, United States.

Who is sponsoring the NCT06455995 clinical trial?

NCT06455995 is sponsored by The University of Tennessee, Knoxville. The trial plans to enroll 174 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology