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Recruiting NCT04678193

COVID-19 Risk Assessment for Hospitalization Outcomes and Epidemiology Efficacy

Trial Parameters

Condition Covid19
Sponsor Aventyn, Inc.
Study Type OBSERVATIONAL
Phase N/A
Enrollment 27,000
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2020-12-24
Completion 2025-06-30
Interventions
Coromec Registry with ECL-19

Brief Summary

Researchers are creating real-time epidemiology registry to evaluate the efficacy of COVID-19 subject risk assessment scores based on recording of symptoms, biomarkers, chronic illness and mental health assessments with digital technology using wearables and mobile app tools. Researchers aim to study in Phase 1, epidemiological variations in COVID-19 presentation in both PCR positive and negative subjects in the registry. Assessment of variables, predictive modeling of variables that impact severity of COVID-19 positive and negative subjects and assessment of predictors for post COVID-19 complications. In Phase 2, 2700 subjects with COVID-19 positive test will be studied in the intervention group comparing ECL-19 vs placebo with primary end point of hospital admission assessment. Treatment strategy for PCR positive COVID-19 subjects in the registry who are in Stage I of the disease process with ECL-19 drug compared to placebo in reducing hospital admissions

Eligibility Criteria

Inclusion Criteria: * COVID-19 PCR positive * COVID-19 PCR negative * COVID-19 PCR pending * COVID-19 high risk score Exclusion Criteria: * Subjects unwilling to participate in the study before, during or after consent * Patients considered unreliable by the investigator concerning the requirements for follow-up visits.

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