NCT06449989 Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer
| NCT ID | NCT06449989 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Blokhin's Russian Cancer Research Center |
| Condition | Colorectal Cancer Metastatic |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2024-04-01 |
| Primary Completion | 2027-09 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2024-04-01 with a primary completion date of 2027-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
GENCONCOR-1 study is translational research aimed to investigate the concordance of the molecular genetic profile of the primary tumor and brain metastases (BM) of colorectal cancer (CRC). The study was conducted by post hoc analysis of pairs of samples of histological material with determination of the mutational status of genes KRAS, NRAS, BRAF, HER2 and MSI.
Eligibility Criteria
Inclusion Criteria: 1. Men and women over 18 years of age. 2. Histologically confirmed cancer of the colon or rectum. 3. Histologically confirmed metastatic lesion of the brain. 4. Neurosurgical resection for brain metastases of colorectal cancer. 5. Presence of paired tumor samples (both primary tumor and intracranial material). Exclusion Criteria: 1. Missing one sample from a pair of tumor samples. 2. Low quality or lack of tumor material for molecular genetic research.
Contact & Investigator
Alexey Tryakin, MD, professor
STUDY CHAIR
Blokhin's Russian Cancer Research Center
Frequently Asked Questions
Who can join the NCT06449989 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Colorectal Cancer Metastatic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06449989 currently recruiting?
Yes, NCT06449989 is actively recruiting participants. Contact the research team at daveupnow@gmail.com for enrollment information.
Where is the NCT06449989 trial being conducted?
This trial is being conducted at Moscow, Russia.
Who is sponsoring the NCT06449989 clinical trial?
NCT06449989 is sponsored by Blokhin's Russian Cancer Research Center. The principal investigator is Alexey Tryakin, MD, professor at Blokhin's Russian Cancer Research Center. The trial plans to enroll 30 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.