NCT07672145 Comparison of Gallbladder Extraction Via Subxiphoid vs Infraumbilical Port in Laparoscopic Cholecystectomy
| NCT ID | NCT07672145 |
| Status | Recruiting |
| Phase | — |
| Sponsor | King Edward Medical University |
| Condition | Cholelithiasis (Without Cholecystitis) |
| Study Type | INTERVENTIONAL |
| Enrollment | 66 participants |
| Start Date | 2026-05-20 |
| Primary Completion | 2026-07-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 66 participants in total. It began in 2026-05-20 with a primary completion date of 2026-07-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Laparoscopic cholecystectomy is the standard surgical treatment for symptomatic gallstone disease due to its advantages in reducing postoperative pain and recovery times. However, surgeons continue to debate the optimal port site for retrieving the gallbladder specimen from the abdominal cavity, as this choice can influence wound-related morbidity. Traditionally, the gallbladder is extracted through the infraumbilical port site. While effective, this route is associated with a potential risk of port-site infections due to bacterial colonization within the umbilicus and risk of contamination during specimen extraction. Retrieving the gallbladder through the subxiphoid port has been proposed as an alternative technique that may utilize a cleaner surgical site, potentially reducing patient pain scores and regional wound complications. This prospective randomized clinical trial aims to directly compare the clinical outcomes of extracting the gallbladder through the subxiphoid port versus the traditional infraumbilical port. The study will evaluate and compare mean postoperative pain intensity within the first 24 hours, as well as the regional development of port-site infections, seromas, or hematomas within 7 days following elective laparoscopic surgery.
Eligibility Criteria
Inclusion Criteria: * Patients aged between 18 to 60 years. * Diagnosed with symptomatic gallstones on ultrasonography. * American Society of Anesthesiologists (ASA) physical status I-II. * Scheduled for elective laparoscopic cholecystectomy. * Presence of acute or empyematous cholecystitis Exclusion Criteria: * Intraoperative conversion to open cholecystectomy. * Diagnosed with Diabetes mellitus type 2.
Contact & Investigator
Dr Muhammad Zeeshan Sarwar, MBBS,FCPS
PRINCIPAL INVESTIGATOR
King Edward Medical University
Frequently Asked Questions
Who can join the NCT07672145 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Cholelithiasis (Without Cholecystitis). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07672145 currently recruiting?
Yes, NCT07672145 is actively recruiting participants. Contact the research team at oabdurrehmanazad@gmail.com for enrollment information.
Where is the NCT07672145 trial being conducted?
This trial is being conducted at Lahore, Pakistan.
Who is sponsoring the NCT07672145 clinical trial?
NCT07672145 is sponsored by King Edward Medical University. The principal investigator is Dr Muhammad Zeeshan Sarwar, MBBS,FCPS at King Edward Medical University. The trial plans to enroll 66 participants.