NCT05632107 Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor
| NCT ID | NCT05632107 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Huazhong University of Science and Technology |
| Condition | Neuromuscular Blockade |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2023-03-01 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2023-03-01 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
A quantitative neuromuscular monitoring device is desirable to titrate the depth of neuromuscular block (NMB) during a procedure, and to prevent residual effects after removal of the endotracheal tube. Unfortunately, the most widely used monitoring technique acceleromyography (AMG) typically implies a series of cumbersome installation and calibration procedures that frequently precludes correct use of these devices in clinical practice. Electromyography (EMG) has recently attracted a lot of attention as an alternative strategy to compensate for the deficiency of AMG-based neuromuscular monitors. Nowadays, a new technology that allows for the simultaneous acquisition of EMG and AMG signals is commercially available. Although its reliability has been rapidly accepted in Physical Medicine and Rehabilitation, the use of the technique in neuromuscular monitoring has never been reported. The aim of the present study is to assess the validity of the new device for estimating the neuromuscular block by comparing with TOF Watch®-SX, which is the most widely accepted AMG-based neuromuscular monitor that has been practiced in the clinical arena for decades.
Eligibility Criteria
Inclusion Criteria: * Age less than 18 yr * American Society of Anesthesiologists Physical Status I to III * Elective surgery requiring muscle relaxation * Patients participated voluntarily and signed informed consent Exclusion Criteria: * Patients with known neuromuscular disorder * Stroke * Patients with a history of allergic reaction toneuromuscular blocking agents * Use of medications that might interfere with neuromuscular transmission * Any previous injury to the examined arm that might influence nerve conduction parameters * Pacemaker
Contact & Investigator
Hua Zheng, Dr.
STUDY DIRECTOR
Department of Anesthesiology, Tongji Hospital
Frequently Asked Questions
Who can join the NCT05632107 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Neuromuscular Blockade. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05632107 currently recruiting?
Yes, NCT05632107 is actively recruiting participants. Contact the research team at hzheng@hust.edu.cn for enrollment information.
Where is the NCT05632107 trial being conducted?
This trial is being conducted at Wuhan, China, Wuhan, China.
Who is sponsoring the NCT05632107 clinical trial?
NCT05632107 is sponsored by Huazhong University of Science and Technology. The principal investigator is Hua Zheng, Dr. at Department of Anesthesiology, Tongji Hospital. The trial plans to enroll 100 participants.