NCT07397117 Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care
| NCT ID | NCT07397117 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, San Francisco |
| Condition | Sciatica Acute |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-05-26 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2026-05-26 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department. The main question it aims to answer is: Is a transgluteal sciatic nerve block better than standard of care in improving pain in ER patients with sciatic back pain? If there is a comparison group: Researchers will compare patients who receive transgluteal sciatic nerve blocks to patients who receive standard of care to see if pain scores improve in ER patients with sciatic back pain. Participants will be randomized into the transgluteal sciatic nerve block group or the control group (standard of care). Participants will be asked to answer questions about their pain and will be asked to walk a timed short distance.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18 years and older * Presentation to ED with: * Acute or acute-on-chronic pain consistent with sciatica, defined as unilateral lumbosacral radicular pain radiating from the lower back or gluteal region to the posterior leg, may extend distal to the knee. * Pain score ≥ 5/10 on Numeric Rating Scale (NRS) Exclusion Criteria: * Known allergy to study medications (e.g., local anesthetics) * Coagulopathy or current anticoagulation therapy * Suspected or confirmed spinal infection, or tumor * Neurological deficits (bowel or bladder dysfunction, leg weakness) * Inability to provide informed consent
Contact & Investigator
Jeanne Noble, MD
PRINCIPAL INVESTIGATOR
University of California, San Francisco
Frequently Asked Questions
Who can join the NCT07397117 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Sciatica Acute. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07397117 currently recruiting?
Yes, NCT07397117 is actively recruiting participants. Contact the research team at tianyu.tang@ucsf.edu for enrollment information.
Where is the NCT07397117 trial being conducted?
This trial is being conducted at San Francisco, United States.
Who is sponsoring the NCT07397117 clinical trial?
NCT07397117 is sponsored by University of California, San Francisco. The principal investigator is Jeanne Noble, MD at University of California, San Francisco. The trial plans to enroll 100 participants.