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Recruiting NCT07180849

NCT07180849 Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.

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Clinical Trial Summary
NCT ID NCT07180849
Status Recruiting
Phase
Sponsor Pakistan Institute of Medical Sciences
Condition Dental Plaque Accumulation
Study Type INTERVENTIONAL
Enrollment 20 participants
Start Date 2025-11
Primary Completion 2027-07

Trial Parameters

Condition Dental Plaque Accumulation
Sponsor Pakistan Institute of Medical Sciences
Study Type INTERVENTIONAL
Phase N/A
Enrollment 20
Sex ALL
Min Age 16 Years
Max Age 30 Years
Start Date 2025-11
Completion 2027-07
Interventions
Fluoride varnishNovel titania nanoparticle infused fluoride varnish

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Brief Summary

In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed orthodontic patients.

Eligibility Criteria

Inclusion criteria: * Patients planned for fixed orthodontic treatment. * Patients within age group 16-30 years. * Patient with no history of previous orthodontic treatment. * Patients with no active periodontal diseases. Exclusion criteria: * Patient undergoing any antibiotic therapy. * Patients with any craniofacial abnormality. * Patient with mixed dentition

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