NCT07158541 Comparing TCAF and MTUN With Soft Tissue Grafting for Treating Single Recessions in the Premandible
| NCT ID | NCT07158541 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Ghent |
| Condition | Gingival Recession, Localized |
| Study Type | INTERVENTIONAL |
| Enrollment | 24 participants |
| Start Date | 2025-08-25 |
| Primary Completion | 2037-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 24 participants in total. It began in 2025-08-25 with a primary completion date of 2037-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Multiple techniques can be used for recession coverage. The most common techniques for single recessions are : tunnel technique (T) and coronally advanced flap (CAF) both combined with a palatal graft to provide sufficient gingival thickness. Recently two modifications have been described in literature, namely the tunneled coronally advanced flap and the modified tunnel. MTUN will function as the control group while people treated with the TCAF technique will function as the test group. This randomized controlled trial compares MTUN and TCAF to determine which technique provides better root coverage for receding gums at single recession in the premandible. The main question it aims to answer is: \- What is the average root coverage achieved with each technique in the short and long term? This may be clinically relevant because covering gum recession can reduce tooth sensitivity, improve aesthetics and make oral hygiene easier. Researchers will compare the modified tunnel technique (MTUN = the gum is undermined) with the tunneled coronally advanced flap (TCAF = the gum is undermined, only partially detached and repositioned higher). In both techniques, a small piece of tissue is removed from the palate, which is used to cover the recession. The purpose of the connective tissue graft under the flap/tunnel, is to increase thickness and provide support. Pain associated to the material used to cover the donorsite will be seen as the secondary research question. The site will either be covered by spongostan and multiple stitches or a palatal stent. Participants will: * Undergo surgery (MTUN or TCAF, randomly assigned) to cover recessions * Attend regular check-ups for up to 10 years after surgery * Keep a postoperative journal (recording medication use, pain levels, tooth sensitivity, etc.)
Eligibility Criteria
Inclusion Criteria: * at least 18 years old * good oral hygiene * presence of one recession in the premandible * good general health Exclusion Criteria: * smoker * pregnant women (assessed at each visit; if the patient appears pregnant during follow-up, x-rays will not be taken)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07158541 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Gingival Recession, Localized. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07158541 currently recruiting?
Yes, NCT07158541 is actively recruiting participants. Contact the research team at vchristi.christiaens@ugent.be for enrollment information.
Where is the NCT07158541 trial being conducted?
This trial is being conducted at Ghent, Belgium.
Who is sponsoring the NCT07158541 clinical trial?
NCT07158541 is sponsored by University Hospital, Ghent. The trial plans to enroll 24 participants.