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Recruiting NCT05729542

NCT05729542 Comparing Clinical Outcomes of Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

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Clinical Trial Summary
NCT ID NCT05729542
Status Recruiting
Phase
Sponsor University of California, San Diego
Condition Ankle Injuries
Study Type INTERVENTIONAL
Enrollment 140 participants
Start Date 2021-11-18
Primary Completion 2026-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Arthrex TightropeSynthes Fibulink

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 140 participants in total. It began in 2021-11-18 with a primary completion date of 2026-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This project consists of a randomized controlled study design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have an acute ankle syndesmosis injury requiring surgery. Patients who consent to study participation will be randomized to receive one of two standard of care procedures - either a suture button or Fibulink implant. Outcome measures, including the Olerud-Molander and American Orthopaedic Foot and Ankle Society scores, pain, range of motion, time to return to work, and radiographic evaluation will be collected for each participant. Given the potential degenerative changes and poor radiographic and clinical outcomes with inadequate repair of the syndesmosis, it is imperative to evaluate existing and emerging methods of fixation for patients with acute ankle fractures with syndesmosis injuries.

Eligibility Criteria

Inclusion Criteria: * Ankle fracture with associated syndesmotic injury requiring surgery * Age 18 years or older * Ability to understand the content of the patient information/informed consent form Exclusion Criteria: * Any not medically managed severe systemic disease * Patient preference for specific implant * Refusal of randomization * Pregnant patients * Prisoners * Participation in any other pharmacologic or medicinal product study within the previous month that could influence the results of this study

Contact & Investigator

Central Contact

Dominic Baun, MS

✉ jbaun@health.ucsd.edu

📞 858-534-8268

Frequently Asked Questions

Who can join the NCT05729542 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Ankle Injuries. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05729542 currently recruiting?

Yes, NCT05729542 is actively recruiting participants. Contact the research team at jbaun@health.ucsd.edu for enrollment information.

Where is the NCT05729542 trial being conducted?

This trial is being conducted at San Diego, United States.

Who is sponsoring the NCT05729542 clinical trial?

NCT05729542 is sponsored by University of California, San Diego. The trial plans to enroll 140 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology