NCT07346326 Comparative Study of Functional Outcomes Between Peroneus Longus and Hamstring Tendon Autografts in Arthroscopic ACL Reconstruction
| NCT ID | NCT07346326 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Khyber Medical University Peshawar |
| Condition | Anterior Cruciate Ligament Injuries |
| Study Type | INTERVENTIONAL |
| Enrollment | 64 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2026-07-28 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 64 participants in total. It began in 2026-01-01 with a primary completion date of 2026-07-28.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a prospective, single-blinded, randomized controlled trial. Sixty patients (≥18 years) with an isolated ACL injury will be randomly assigned to receive an ACL reconstruction using either a Peroneus Longus Tendon (PLT) autograft or a Hamstring Tendon (HST) autograft. The primary objective is to compare early functional outcomes between the two groups at 6 weeks and 3 months post-surgery, using the Lysholm Knee Score. The study aims to demonstrate the non-inferiority of the PLT graft. All surgeries will be performed arthroscopically at Khyber Teaching Hospital, Peshawar, followed by a standardized rehabilitation protocol.
Eligibility Criteria
Inclusion Criteria: * Patients aged 18 years or older. * Isolated, primary Anterior Cruciate Ligament (ACL) injury confirmed by clinical assessment and Magnetic Resonance Imaging (MRI). * Provides written informed consent for the surgical procedure and study participation, including follow-up assessments. Exclusion Criteria: * Multiligament knee injuries (e.g., concomitant PCL, MCL, or LCL injuries). * Previous surgery or history of fracture in the involved lower limb. * Radiographic evidence of osteoarthritis in the affected knee. * Presence of any neuromuscular disease.
Contact & Investigator
Dr Syed Dil Bagh Ali Shah, MBBS
PRINCIPAL INVESTIGATOR
Khyber Teaching Hospital
Frequently Asked Questions
Who can join the NCT07346326 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Anterior Cruciate Ligament Injuries. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07346326 currently recruiting?
Yes, NCT07346326 is actively recruiting participants. Contact the research team at drdilbagh@icloud.com for enrollment information.
Where is the NCT07346326 trial being conducted?
This trial is being conducted at Peshawar, Pakistan.
Who is sponsoring the NCT07346326 clinical trial?
NCT07346326 is sponsored by Khyber Medical University Peshawar. The principal investigator is Dr Syed Dil Bagh Ali Shah, MBBS at Khyber Teaching Hospital. The trial plans to enroll 64 participants.